NETosis and neutrophil extracellular traps in COVID-19: immunothrombosis and beyond

Y Zhu, X Chen, X Liu - Frontiers in Immunology, 2022 - frontiersin.org
Infection with SARS-CoV-2, the causative agent of the Coronavirus disease 2019 (COVID-
19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial …

Multifunctional role of S100 protein family in the immune system: an update

P Singh, SA Ali - Cells, 2022 - mdpi.com
S100 is a broad subfamily of low-molecular weight calcium-binding proteins (9–14 kDa) with
structural similarity and functional discrepancy. It is required for inflammation and cellular …

Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection

L Ma, SK Sahu, M Cano, V Kuppuswamy, J Bajwa… - Science …, 2021 - science.org
Complement activation has been implicated in the pathogenesis of severe SARS-CoV-2
infection. However, it remains to be determined whether increased complement activation is …

A persistent neutrophil-associated immune signature characterizes post–COVID-19 pulmonary sequelae

PM George, A Reed, SR Desai, A Devaraj… - Science translational …, 2022 - science.org
Interstitial lung disease and associated fibrosis occur in a proportion of individuals who have
recovered from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

Trapped ion mobility spectrometry and parallel accumulation–serial fragmentation in proteomics

F Meier, MA Park, M Mann - Molecular & Cellular Proteomics, 2021 - ASBMB
Recent advances in efficiency and ease of implementation have rekindled interest in ion
mobility spectrometry, a technique that separates gas phase ions by their size and shape …

Increased peripheral blood neutrophil activation phenotypes and neutrophil extracellular trap formation in critically ill coronavirus disease 2019 (COVID-19) patients: a …

JA Masso-Silva, A Moshensky, MTY Lam… - Clinical Infectious …, 2022 - academic.oup.com
Background Increased inflammation has been well defined in coronavirus disease 2019
(COVID-19), while definitive pathways driving severe forms of this disease remain uncertain …

Plasma proteomic signature predicts who will get persistent symptoms following SARS-CoV-2 infection

G Captur, JC Moon, CC Topriceanu, G Joy… - …, 2022 - thelancet.com
Background The majority of those infected by ancestral Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2) during the UK first wave (starting March 2020) did not require …

A clinical-stage cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells

DM Mellott, CT Tseng, A Drelich, P Fajtová… - ACS chemical …, 2021 - ACS Publications
Host-cell cysteine proteases play an essential role in the processing of the viral spike protein
of SARS coronaviruses. K777, an irreversible, covalent inactivator of cysteine proteases that …

Role of senescence and aging in SARS-CoV-2 infection and COVID-19 disease

SM Lynch, G Guo, DS Gibson, AJ Bjourson, TS Rai - Cells, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has resulted in a global pandemic associated with substantial …

Molecular diagnostic assays for COVID-19: an overview

P Habibzadeh, M Mofatteh, M Silawi… - Critical reviews in …, 2021 - Taylor & Francis
Abstract The coronavirus disease 2019 (COVID-19) pandemic has highlighted the cardinal
importance of rapid and accurate diagnostic assays. Since the early days of the outbreak …