Macrophage migration inhibitory factor (MIF): a multifaceted cytokine regulated by genetic and physiological strategies
Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine encoded within a
functionally polymorphic genetic locus. MIF was initially recognized as a cytokine generated …
functionally polymorphic genetic locus. MIF was initially recognized as a cytokine generated …
The biological function and significance of CD74 in immune diseases
Abstract CD74 (MHC class II invariant chain, Ii) is a non-polymorphic type II transmembrane
glycoprotein. It is clear that, in addition to be an MHC class II chaperone, CD74 has a …
glycoprotein. It is clear that, in addition to be an MHC class II chaperone, CD74 has a …
Macrophage migration inhibitory factor: a regulator of innate immunity
For more than a quarter of a century, macrophage migration inhibitory factor (MIF) has been
a mysterious cytokine. In recent years, MIF has assumed an important role as a pivotal …
a mysterious cytokine. In recent years, MIF has assumed an important role as a pivotal …
MIF signal transduction initiated by binding to CD74
Macrophage migration inhibitory factor (MIF) accounts for one of the first cytokine activities to
have been described, and it has emerged recently to be an important regulator of innate and …
have been described, and it has emerged recently to be an important regulator of innate and …
The pathogenesis of oral lichen planus
Both antigen-specific and non-specific mechanisms may be involved in the pathogenesis of
oral lichen planus (OLP). Antigen-specific mechanisms in OLP include antigen presentation …
oral lichen planus (OLP). Antigen-specific mechanisms in OLP include antigen presentation …
Allergy diagnostic testing: an updated practice parameter
The major emphasis of this updated version of Practice Parameters for Allergy Diagnostic
Testing is focused on how technological refinements and their validations during the past …
Testing is focused on how technological refinements and their validations during the past …
An essential regulatory role for macrophage migration inhibitory factor in T-cell activation.
The protein known as macrophage migration inhibitory factor (MIF) was one of the first
cytokines to be discovered and was described 30 years ago to be a T-cell-derived factor that …
cytokines to be discovered and was described 30 years ago to be a T-cell-derived factor that …
An inflammatory review of glucocorticoid actions in the CNS
In recent years, the classic view that glucocorticoids, the adrenal steroids secreted during
stress, are universally anti-inflammatory has been challenged at a variety of levels. It was …
stress, are universally anti-inflammatory has been challenged at a variety of levels. It was …
Sustained mitogen-activated protein kinase (MAPK) and cytoplasmic phospholipase A2 activation by macrophage migration inhibitory factor (MIF): regulatory role in …
Macrophage migration inhibitory factor (MIF) is an important pro-inflammatory mediator with
the unique ability to counter-regulate the inhibitory effects of glucocorticoids on immune cell …
the unique ability to counter-regulate the inhibitory effects of glucocorticoids on immune cell …
Exploring the anti‐inflammatory activity of sulforaphane
Dysregulation of innate immune responses can result in chronic inflammatory conditions.
Glucocorticoids, the current frontline therapy, are effective immunosuppressive drugs but …
Glucocorticoids, the current frontline therapy, are effective immunosuppressive drugs but …