Cortical networks are composed of glutamatergic excitatory projection neurons and local
GABAergic inhibitory interneurons that gate signal flow and sculpt network dynamics …

Mammals adapt to a rapidly changing world because of the sophisticated cognitive functions
that are supported by the neocortex. The neocortex, which forms almost 80% of the human …

Neurons in the brain communicate by short electrical pulses, the so-called action potentials
or spikes. How can we understand the process of spike generation? How can we …

Neuronal circuits in the brain are shaped by experience during'critical periods' in early
postnatal life. In the primary visual cortex, this activity-dependent development is triggered …

This book aims to provide an introduction to dynamical systems with multiple time scales. As
in any overview book, several topics are covered only quite briefly. My aim was to focus on …

In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

The action potential of the squid giant axon is formed by just two voltage-dependent
conductances in the cell membrane, yet mammalian central neurons typically express more …

Cognitive deficits are a core clinical feature of schizophrenia but respond poorly to available
medications. Thus, understanding the neural basis of these deficits is crucial for the …

Abstract Analysis of the Kv3 subfamily of K+ channel subunits has lead to the discovery of a
new class of neuronal voltage-gated K+ channels characterized by positively shifted voltage …

The cortex contains multiple cell types, but studies of attention have not distinguished
between them, limiting understanding of the local circuits that transform attentional feedback …