Multifaceted role of phyto-derived polyphenols in nanodrug delivery systems

Z Chen, MA Farag, Z Zhong, C Zhang, Y Yang… - Advanced drug delivery …, 2021 - Elsevier
As naturally occurring bioactive products, several lines of evidence have shown the potential
of polyphenols in the medical intervention of various diseases, including tumors …

Oral nanomedicine: challenges and opportunities

B Deng, S Liu, Y Wang, B Ali, N Kong, T **e… - Advanced …, 2024 - Wiley Online Library
Compared to injection administration, oral administration is free of discomfort, wound
infection, and complications and has a higher compliance rate for patients with diverse …

Wielding the double-edged sword: Redox drug delivery systems for inflammatory bowel disease

Y Chen, M Shui, Q Yuan, CT Vong, Z Yang… - Journal of Controlled …, 2023 - Elsevier
The etiology of inflammatory bowel disease (IBD) is extremely complex and related to an
excessive immune response that results in the pathologically release of reactive oxygen …

Biomaterials as therapeutic drug carriers for inflammatory bowel disease treatment

CPJ Wang, MJ Byun, SN Kim, W Park, HH Park… - Journal of Controlled …, 2022 - Elsevier
Inflammatory bowel diseases (IBDs) are idiopathic gastrointestinal inflammatory disorders
featuring chronic intestinal inflammation. Although IBDs are increasingly becoming globally …

Gram-scale preparation of quercetin supramolecular nanoribbons for intestinal inflammatory diseases by oral administration

W Sun, Y Chen, L Wang, Z Wang, S Liu, M Zhang… - Biomaterials, 2023 - Elsevier
Gastrointestinal (GI) tract, which possesses the largest surface area of mucosa in the body,
is easily suffered from inflammatory damages under the exposure of external stimulations …

Improving silymarin oral bioavailability using silica-installed redox nanoparticle to suppress inflammatory bowel disease

THT Nguyen, NT Trinh, HN Tran, HT Tran, PQ Le… - Journal of controlled …, 2021 - Elsevier
Chronic inflammatory diseases such as inflammatory bowel diseases (IBD), which are
strongly related to the overproduction of reactive oxygen species (ROS), have become more …

Flexible inorganic core-shell nanofibers endowed with tunable multicolor upconversion fluorescence for simultaneous monitoring dual drug delivery

J Zhang, S Li, DD Ju, X Li, JC Zhang, X Yan… - Chemical Engineering …, 2018 - Elsevier
Simultaneous monitoring multiple drug delivery with different drug ratios can obtain the real-
time relationship between drug ratios and therapeutic effects, which can accelerate the …

Orally delivered antisense oligodeoxyribonucleotides of TNF‐α via polysaccharide‐based nanocomposites targeting intestinal inflammation

B Duan, M Li, Y Sun, S Zou, X Xu - Advanced healthcare …, 2019 - Wiley Online Library
Tumor necrosis factor alpha (TNF‐α) is usually regarded as a potential target for
inflammatory bowel disease therapy. Herein, a promising strategy for effective delivery of …

Redox nanoparticles: synthesis, properties and perspectives of use for treatment of neurodegenerative diseases

I Sadowska-Bartosz, G Bartosz - Journal of Nanobiotechnology, 2018 - Springer
Oxidative stress (OS) and nitrative stress (NS) accompany many diseases, including
Alzheimer's disease (AD) and Parkinson's disease (PD). Antioxidants have been proposed …

A silica-based antioxidant nanoparticle for oral delivery of Camptothecin which reduces intestinal side effects while improving drug efficacy for colon cancer treatment

QN Nguyen-Trinh, KXT Trinh, NT Trinh, N Li… - Acta Biomaterialia, 2022 - Elsevier
Camptothecin (CPT) is a potent anticancer agent for the treatment of colorectal cancer;
however, it exhibits some limitations, including poor solubility, low stability, and low …