Update on degenerative ataxias

T Klockgether - Current opinion in neurology, 2011 - journals.lww.com
Update on degenerative ataxias : Current Opinion in Neurology Update on degenerative
ataxias : Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe Get …

Diffusion-MRI in neurodegenerative disorders

J Goveas, L O'Dwyer, M Mascalchi, M Cosottini… - Magnetic resonance …, 2015 - Elsevier
The ability to image the whole brain through ever more subtle and specific
methods/contrasts has come to play a key role in understanding the basis of brain …

[HTML][HTML] Autosomal dominant cerebellar ataxias: imaging biomarkers with high effect sizes

IM Adanyeguh, V Perlbarg, PG Henry, D Rinaldi… - NeuroImage: Clinical, 2018 - Elsevier
Objective As gene-based therapies may soon arise for patients with spinocerebellar ataxia
(SCA), there is a critical need to identify biomarkers of disease progression with effect sizes …

Morphometric analyses of the visual pathways in macular degeneration

AT Hernowo, D Prins, HA Baseler, T Plank, AD Gouws… - Cortex, 2014 - Elsevier
Introduction Macular degeneration (MD) causes central visual field loss. When field defects
occur in both eyes and overlap, parts of the visual pathways are no longer stimulated …

Cerebral abnormalities in Friedreich ataxia: a review

LP Selvadurai, IH Harding, LA Corben… - Neuroscience & …, 2018 - Elsevier
Friedreich ataxia (FRDA) is an inherited degenerative disorder affecting multiple systems of
the body and resulting in symptoms which include progressive ataxia, dysarthria, and …

Depression disorder in patients with cerebellar damage: Awareness of the mood state.

S Clausi, M Lupo, G Olivito, L Siciliano… - Journal of Affective …, 2019 - Elsevier
Background Although depressive symptoms are often reported to be comorbid with
degenerative cerebellar diseases, the role of the cerebellum in depressive disorder needs to …

[HTML][HTML] Training-induced improvements in postural control are accompanied by alterations in cerebellar white matter in brain injured patients

D Drijkoningen, K Caeyenberghs, I Leunissen… - NeuroImage: Clinical, 2015 - Elsevier
We investigated whether balance control in young TBI patients can be promoted by an 8-
week balance training program and whether this is associated with neuroplastic alterations …

SCA7 mouse cerebellar pathology reveals preferential downregulation of key Purkinje cell-identity genes and shared disease signature with SCA1 and SCA2

A Niewiadomska-Cimicka, F Doussau… - Journal of …, 2021 - Soc Neuroscience
Spinocerebellar ataxia type 7 (SCA7) is an inherited neurodegenerative disease mainly
characterized by motor incoordination because of progressive cerebellar degeneration …

MR imaging of sca3/mjd

N Wan, Z Chen, L Wan, B Tang, H Jiang - Frontiers in neuroscience, 2020 - frontiersin.org
Spinocerebellar ataxia type 3/Machado–Joseph disease (SCA3/MJD) is a progressive
autosomal dominantly inherited cerebellar ataxia characterized by the aggregation of …

A multimodal evaluation of microstructural white matter damage in spinocerebellar ataxia type 3

RP Guimarães, A D'Abreu, CL Yasuda… - Movement …, 2013 - Wiley Online Library
Although white matter damage may play a major role in the pathogenesis of spinocerebellar
ataxia 3 (SCA3), available data rely exclusively upon macrostructural analyses. In this …