Traumatic brain injury and risk of neurodegenerative disorder

BL Brett, RC Gardner, J Godbout, K Dams-O'Connor… - Biological …, 2022 - Elsevier
Traumatic brain injury (TBI), particularly of greater severity (ie, moderate to severe), has
been identified as a risk factor for all-cause dementia and Parkinson's disease, with risk for …

Epidemiology of chronic effects of traumatic brain injury

J Haarbauer-Krupa, MJ Pugh, EM Prager… - Journal of …, 2021 - liebertpub.com
Although many patients diagnosed with traumatic brain injury (TBI), particularly mild TBI,
recover from their symptoms within a few weeks, a small but meaningful subset experience …

[HTML][HTML] Global, regional, and national burden of Parkinson's disease, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

ER Dorsey, A Elbaz, E Nichols, N Abbasi… - The Lancet …, 2018 - thelancet.com
Background Neurological disorders are now the leading source of disability globally, and
ageing is increasing the burden of neurodegenerative disorders, including Parkinson's …

Neurodegenerative disease among male elite football (soccer) players in Sweden: a cohort study

P Ueda, B Pasternak, CE Lim, M Neovius… - The Lancet Public …, 2023 - thelancet.com
Background Football (soccer) players might be at increased risk of neurodegenerative
disease, which has led to questions regarding the safety of the sport and recent measures …

Neuroinflammation represents a common theme amongst genetic and environmental risk factors for Alzheimer and Parkinson diseases

RJ Boyd, D Avramopoulos, LL Jantzie… - Journal of …, 2022 - Springer
Multifactorial diseases are characterized by inter-individual variation in etiology, age of
onset, and penetrance. These diseases tend to be relatively common and arise from the …

Understanding neurodegeneration after traumatic brain injury: from mechanisms to clinical trials in dementia

NSN Graham, DJ Sharp - Journal of Neurology, Neurosurgery & …, 2019 - jnnp.bmj.com
Traumatic brain injury (TBI) leads to increased rates of dementia, including Alzheimer's
disease. The mechanisms by which trauma can trigger neurodegeneration are increasingly …

The synapse in traumatic brain injury

AAB Jamjoom, J Rhodes, PJD Andrews, SGN Grant - Brain, 2021 - academic.oup.com
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide and is a risk
factor for dementia later in life. Research into the pathophysiology of TBI has focused on the …

Linking environmental risk factors with epigenetic mechanisms in Parkinson's disease

M Tsalenchuk, SM Gentleman, SJ Marzi - npj Parkinson's Disease, 2023 - nature.com
Sporadic Parkinson's disease (PD) is a progressive neurodegenerative disease, with a
complex risk structure thought to be influenced by interactions between genetic variants and …

Risk of posttraumatic stress disorder and major depression in civilian patients after mild traumatic brain injury: a TRACK-TBI study

MB Stein, S Jain, JT Giacino, H Levin, S Dikmen… - JAMA …, 2019 - jamanetwork.com
Importance Traumatic brain injury (TBI) has been associated with adverse mental health
outcomes, such as posttraumatic stress disorder (PTSD) and major depressive disorder …

COVID-19 and long COVID: disruption of the neurovascular unit, blood-brain barrier, and tight junctions

D Kempuraj, KK Aenlle, J Cohen… - The …, 2024 - journals.sagepub.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease 2019 (COVID-19), could affect brain structure and function. SARS-CoV …