The neuromuscular junction in health and disease: molecular mechanisms governing synaptic formation and homeostasis

PM Rodríguez Cruz, J Cossins, D Beeson… - Frontiers in molecular …, 2020 - frontiersin.org
The neuromuscular junction (NMJ) is a highly specialized synapse between a motor neuron
nerve terminal and its muscle fiber that are responsible for converting electrical impulses …

Neuromuscular junction formation, aging, and disorders

L Li, WC ** neuromuscular junctions
P Alvarez-Suarez, M Gawor, TJ Prószyński - Seminars in Cell & …, 2020 - Elsevier
Neuromuscular junctions (NMJs) are specialized synapses in the peripheral nervous system
that allow the transmission of neuronal impulses to skeletal muscles for their contraction …

Murine muscle stem cell response to perturbations of the neuromuscular junction are attenuated with aging

JA Larouche, M Mohiuddin, JJ Choi, PJ Ulintz… - Elife, 2021 - elifesciences.org
During aging and neuromuscular diseases, there is a progressive loss of skeletal muscle
volume and function impacting mobility and quality of life. Muscle loss is often associated …

C9orf72 functions in the nucleus to regulate DNA damage repair

L He, J Liang, C Chen, J Chen, Y Shen… - Cell Death & …, 2023 - nature.com
The hexanucleotide GGGGCC repeat expansion in the intronic region of C9orf72 is the most
common cause of Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) …