Most antimalarials are based on basic N-heterocycles and possess amine functionalities.
Despite this, the role of basic nitrogen (BaN) in antimalarial drug design has not been …

A substantial challenge worldwide is emergent drug resistance in malaria parasites against
approved drugs, such as chloroquine (CQ). To address these unsolved CQ resistance …

A synthetic protocol was developed to synthesize highly functionalized 3‐furylmethyl
chromones from enynones and o‐hydroxyphenyl enaminones via silver‐catalyzed cascade …

The global challenge to the treatment of malaria is mainly the occurrence of resistance of
malaria parasites to conventionally used antimalarials. Artesunate, a semisynthetic …

ABSTRACT According to the World Health Organization, malaria remains one of the biggest
public health problems in the world. The development of resistance is a current concern …

A silver‐catalyzed protocol for the synthesis of 3‐(1H‐isochromen)‐chromones is described.
The method involves an initial 6‐endo‐dig cyclization of o‐alkynylbenzaldehydes and …

Based on medicinal chemistry tools, new compounds for malaria treatment were designed.
The scaffolds of the drugs used to treat malaria, such as chloroquine, primaquine …

A range of antimicrobial peptides (AMP) exhibit activity on malaria parasites, Plasmodium
spp., in their blood or mosquito stages, or both. These peptides include a diverse array of …

Acridine frameworks stand as pivotal architectural elements in pharmaceuticals and
photocatalytic applications, owing to their chemical adaptability, biological activity, and …

Malaria remains a major vector borne disease claiming millions of lives worldwide due to
infections caused by Plasmodium sp. Discovery and development of antimalarial drugs have …