Cellular senescence in brain aging and cognitive decline

A Shafqat, S Khan, MH Omer, M Niaz… - Frontiers in aging …, 2023 - frontiersin.org
Cellular senescence is a biological aging hallmark that plays a key role in the development
of neurodegenerative diseases. Clinical trials are currently underway to evaluate the …

The role of aging in Intracerebral Hemorrhage

B Huang, A Chen, Y Sun, Q He - Brain Sciences, 2024 - mdpi.com
Intracerebral hemorrhage (ICH) is the cerebrovascular disease with the highest disability
and mortality rates, causing severe damage to the health of patients and imposing a …

Chronic kidney disease promotes cerebral microhemorrhage formation

C Fang, WL Lau, J Sun, R Chang, A Vallejo… - Journal of …, 2023 - Springer
Background Chronic kidney disease (CKD) is increasingly recognized as a stroke risk factor,
but its exact relationship with cerebrovascular disease is not well-understood. We …

[HTML][HTML] CKD progression prediction in a diverse US population: a machine-learning model

J Aoki, C Kaya, O Khalid, T Kothari, MA Silberman… - Kidney Medicine, 2023 - Elsevier
Rationale & Objective Chronic kidney disease (CKD) is a major cause of morbidity and
mortality. To date, there are no widely used machine-learning models that can predict …

[HTML][HTML] Evolving patterns of intracranial hemorrhage in advanced therapies in patients with acute pulmonary embolism

KC Christodoulou, K Mohr, T Uphaus, M Jägersberg… - Thrombosis …, 2024 - Elsevier
Background Dissecting trends and contributing risk factors for intracranial hemorrhage (ICH)
in patients treated for acute pulmonary embolism (PE) may allow for a better patient …

Association of aspirin use with risk of intracerebral hemorrhage in patients without history of stroke or transient ischemic attack in the UK Biobank

Z Wang, X Liu, S Zhang, X Hu… - International Journal of …, 2025 - journals.sagepub.com
Background: The association between aspirin use and the risk of intracerebral hemorrhage
(ICH) among individuals without previous stroke events is inconclusive. Aim: We …

Associations of cerebral small vessel disease and chronic kidney disease in patients with acute intracerebral hemorrhage: a cross-sectional study

PS Nash, S Fandler-Höfler, G Ambler, W Zhang… - Neurology, 2024 - neurology.org
Background and Objectives Chronic kidney disease (CKD) may be associated with the
pathogenesis and phenotype of cerebral small vessel disease (SVD), which is the …

Genetics of intracerebral hemorrhage

TN Kimball, RWP Tack, A Chen… - Journal of Cerebral …, 2025 - journals.sagepub.com
Spontaneous intracerebral hemorrhage (ICH) represents a life-threatening form of stroke,
marked by its impact on survival and quality of life. ICH can be categorized from monogenic …

Unveiling the Hidden Impact: Hematoma Volumes Unravel Circuit Disruptions in Intracerebral Hemorrhage

Y Wu, Q Deng, R Wei, S Chen, F Ding, H Yu… - Translational Stroke …, 2024 - Springer
Intracerebral hemorrhage (ICH) imposes a significant burden on patients, and the volume of
hematoma plays a crucial role in determining the severity and prognosis of ICH. Although …

Anticoagulant therapy in renal insufficiency theme: Anticoagulation in complex situations

AL Parks, SM Stevens, SC Woller - Thrombosis Research, 2024 - Elsevier
Many patients with impaired renal function have concurrent indications for anticoagulant
therapy, including atrial fibrillation and venous thromboembolism. For mild chronic kidney …