Preeclampsia: Recent advances in predicting, preventing, and managing the maternal and fetal life-threatening condition

KJ Chang, KM Seow, KH Chen - International journal of environmental …, 2023 - mdpi.com
Preeclampsia accounts for one of the most common documented gestational complications,
with a prevalence of approximately 2 to 15% of all pregnancies. Defined as gestational …

[HTML][HTML] Role of oxidative stress in the dysfunction of the placental endothelial nitric oxide synthase in preeclampsia

P Guerby, O Tasta, A Swiader, F Pont, E Bujold… - Redox biology, 2021 - Elsevier
Preeclampsia (PE) is a multifactorial pregnancy disease, characterized by new-onset
gestational hypertension with (or without) proteinuria or end-organ failure, exclusively …

The exciting potential for ChatGPT in obstetrics and gynecology

A Grünebaum, J Chervenak, SL Pollet, A Katz… - American Journal of …, 2023 - Elsevier
Natural language processing—the branch of artificial intelligence concerned with the
interaction between computers and human language—has advanced markedly in recent …

The 2021 International Society for the Study of Hypertension in Pregnancy classification, diagnosis & management recommendations for international practice

LA Magee, MA Brown, DR Hall, S Gupte… - Pregnancy …, 2022 - Elsevier
All units managing hypertensive pregnant women should maintain and review uniform
departmental management protocols and conduct regular audits of maternal & fetal …

Preeclampsia pathophysiology and adverse outcomes during pregnancy and postpartum

C Bisson, S Dautel, E Patel, S Suresh, P Dauer… - Frontiers in …, 2023 - frontiersin.org
Background Preeclampsia is a disease with far-reaching consequences that extend beyond
the immediate postpartum period and have a significant impact later in life. Preeclampsia …

Biological and pathological mechanisms leading to the birth of a small vulnerable newborn

PJ Hunter, T Awoyemi, AI Ayede, RM Chico, AL David… - The Lancet, 2023 - thelancet.com
The pathway to a thriving newborn begins before conception and continues in utero with a
healthy placenta and the right balance of nutrients and growth factors that are timed and …

[HTML][HTML] Toward a new taxonomy of obstetrical disease: improved performance of maternal blood biomarkers for the great obstetrical syndromes when classified …

R Romero, E Jung, T Chaiworapongsa, O Erez… - American journal of …, 2022 - Elsevier
Background The major challenge for obstetrics is the prediction and prevention of the great
obstetrical syndromes. We propose that defining obstetrical diseases by the combination of …

Aspirin discontinuation at 24 to 28 weeks' gestation in pregnancies at high risk of preterm preeclampsia: a randomized clinical trial

M Mendoza, E Bonacina, P Garcia-Manau, M López… - Jama, 2023 - jamanetwork.com
Importance Aspirin reduces the incidence of preterm preeclampsia by 62% in pregnant
individuals at high risk of preeclampsia. However, aspirin might be associated with an …

A randomized pilot clinical trial of pravastatin versus placebo in pregnant patients at high risk of preeclampsia

MM Costantine, H West, KL Wisner, S Caritis… - American journal of …, 2021 - Elsevier
Background Preeclampsia remains a major cause of maternal and neonatal morbidity and
mortality. Biologic plausibility, compelling preliminary data, and a pilot clinical trial support …

An overview of obesity, cholesterol, and systemic inflammation in preeclampsia

MC Alston, LM Redman, JL Sones - Nutrients, 2022 - mdpi.com
Preeclampsia (PE), an inflammatory state during pregnancy, is a significant cause of
maternal and fetal morbidity and mortality. Adverse outcomes associated with PE include …