Formation of mRNA 3′ ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis
J Zhao, L Hyman, C Moore - Microbiology and molecular biology …, 1999 - Am Soc Microbiol
Formation of mRNA 3′ ends in eukaryotes requires the interaction of transacting factors
with cis-acting signal elements on the RNA precursor by two distinct mechanisms, one for …
with cis-acting signal elements on the RNA precursor by two distinct mechanisms, one for …
RNA polymerase II and the integration of nuclear events
Y Hirose, JL Manley - Genes & development, 2000 - genesdev.cshlp.org
The synthesis of a messenger RNA in the nucleus of a eukaryotic cell is an immensely
complex undertaking. Each step in the pathway requires an enormous number of protein …
complex undertaking. Each step in the pathway requires an enormous number of protein …
Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins
The reversible protein phosphorylation on serine or threonine residues that precede proline
(pSer/Thr-Pro) is a key signaling mechanism for the control of various cellular processes …
(pSer/Thr-Pro) is a key signaling mechanism for the control of various cellular processes …
[HTML][HTML] Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c‐Jun towards cyclin D1
GM Wulf, A Ryo, GG Wulf, SW Lee, T Niu… - The EMBO …, 2001 - embopress.org
Phosphorylation on serines or threonines preceding proline (Ser/Thr‐Pro) is a major
signaling mechanism. The conformation of a subset of phosphorylated Ser/Thr‐Pro motifs is …
signaling mechanism. The conformation of a subset of phosphorylated Ser/Thr‐Pro motifs is …
Structural basis for phosphoserine-proline recognition by group IV WW domains
Pin1 contains an N-terminal WW domain and a C-terminal peptidyl-prolyl cis-trans
isomerase (PPIase) domain connected by a flexible linker. To address the energetic and …
isomerase (PPIase) domain connected by a flexible linker. To address the energetic and …
Requirement of the Inositol Trisphosphate Receptor for Activation of Store-Operated Ca2+ Channels
The coupling mechanism between endoplasmic reticulum (ER) calcium ion (Ca2+) stores
and plasma membrane (PM) store-operated channels (SOCs) is crucial to Ca2+ signaling …
and plasma membrane (PM) store-operated channels (SOCs) is crucial to Ca2+ signaling …
Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser 2 of the RNA polymerase II C-terminal domain
The C-terminal domain (CTD) of the RNA polymerase II (Pol II) largest subunit is
hyperphosphorylated during transcription. Using an in vivo cross-linking/chromatin …
hyperphosphorylated during transcription. Using an in vivo cross-linking/chromatin …
Pinning down proline-directed phosphorylation signaling
The reversible phosphorylation of proteins on serine or threonine residues preceding
proline (Ser/Thr-Pro) is a major cellular signaling mechanism. Although it is proposed that …
proline (Ser/Thr-Pro) is a major cellular signaling mechanism. Although it is proposed that …
Functional interaction of yeast pre-mRNA 3′ end processing factors with RNA polymerase II
Abstract The RNA polymerase II CTD is essential for 3′ end cleavage of metazoan pre-
mRNAs and binds 3′ end processing factors in vitro. We show genetic and biochemical …
mRNAs and binds 3′ end processing factors in vitro. We show genetic and biochemical …
RNA polymerase II C-terminal domain: tethering transcription to transcript and template
JL Corden - Chemical reviews, 2013 - ACS Publications
By definition the CTD consists of the amino acid sequences extending from the largest
subunit, RPO21 or RPB1 in yeast and POLR2A in human. Specifically the CTD consists of …
subunit, RPO21 or RPB1 in yeast and POLR2A in human. Specifically the CTD consists of …