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Friend or foe: the role of stress granule in neurodegenerative disease
Q Cui, Z Liu, G Bai - Neuron, 2024 - cell.com
Stress granules (SGs) are dynamic membraneless organelles that form in response to
cellular stress. SGs are predominantly composed of RNA and RNA-binding proteins that …
cellular stress. SGs are predominantly composed of RNA and RNA-binding proteins that …
Membraneless organelles in health and disease: exploring the molecular basis, physiological roles and pathological implications
Y Li, Y Liu, XY Yu, Y Xu, X Pan, Y Sun… - … and Targeted Therapy, 2024 - nature.com
Once considered unconventional cellular structures, membraneless organelles (MLOs),
cellular substructures involved in biological processes or pathways under physiological …
cellular substructures involved in biological processes or pathways under physiological …
µMap proximity labeling in living cells reveals stress granule disassembly mechanisms
Phase-separated condensates are membrane-less intracellular structures comprising
dynamic protein interactions that organize essential biological processes. Understanding …
dynamic protein interactions that organize essential biological processes. Understanding …
[HTML][HTML] hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility
X Wang, X Fan, J Zhang, F Wang, J Chen, Y Wen… - Cell Reports, 2024 - cell.com
Although the composition and assembly of stress granules (SGs) are well understood, the
molecular mechanisms underlying SG disassembly remain unclear. Here, we identify that …
molecular mechanisms underlying SG disassembly remain unclear. Here, we identify that …
Stress granules and organelles: Coordinating cellular responses in health and disease
Y Liu, Y Li, P Zhang - Protein & Cell, 2024 - academic.oup.com
Membrane-bound organelles and membraneless organelles (MLOs) coordinate various
biological processes within eukaryotic cells. Among these, stress granules (SGs) are …
biological processes within eukaryotic cells. Among these, stress granules (SGs) are …
RNF220-mediated K63-linked polyubiquitination stabilizes Olig proteins during oligodendroglial development and myelination
Y Li, LP Wan, NN Song, YQ Ding, S Zhao, J Niu… - Science …, 2024 - science.org
Maldevelopment of oligodendroglia underlies neural developmental disorders such as
leukodystrophy. Precise regulation of the activity of specific transcription factors (TFs) by …
leukodystrophy. Precise regulation of the activity of specific transcription factors (TFs) by …
Global discovery of covalent modulators of ribonucleoprotein granules
Stress granules (SGs) and processing-bodies (PBs, P-bodies) are ubiquitous and widely
studied ribonucleoprotein (RNP) granules involved in cellular stress response, viral …
studied ribonucleoprotein (RNP) granules involved in cellular stress response, viral …