The tumor microenvironment (TME) controls tumor progression and maintenance.
Accordingly, tumor-centric cancer treatment must adjust to being more holistic and TME …

Background Collagen dominates the skin's extracellular matrix (ECM). Type I collagen
comprises 80%–90% of the skin's collagen, followed by type III (8%–12%) and type V (5%) …

Hyaluronic acid (HA) and proteoglycans (such as dermatan sulphate (DS) and chondroitin
sulphate (CS)) are the main components of the extracellular matrix of the skin, along with …

Zinc (Zn) is a new class of bioresorbable metal that has potential for cardiovascular stent
material, orthopedic implants, wound closure devices, etc. However, pure Zn is not ideal for …

Simple Summary During the development of solid cancers, the ECM undergoes significant
changes in composition and function that facilitate the growth and spread of cancer cells. To …

Wound healing is a complicated process for maintaining skin integrity after injury, for which
electrical stimulations (ES) have been attributed to promote wound healing by facilitating cell …

Zinc-based alloys, specifically Zn–Mg, have garnered considerable attention as promising
materials for biodegradable implants due to their favorable mechanical strength, appropriate …

Introduction Diabetic foot ulcer (DFU) is a severe complication that threatens the daily lives
of patients with diabetes and represents a serious challenge to the global health system …

Cardiac fibrosis, which is the buildup of proteins in the connective tissues of the heart, can
lead to end-stage extracellular matrix (ECM) remodeling and ultimately heart failure. Cardiac …

Human skin is constructed with many proteins such as collagen and elastin. Collagen and
elastin play a key role in providing strength and elasticity to the human skin and body …