EMT factors and metabolic pathways in cancer

I Georgakopoulos-Soares, DV Chartoumpekis… - Frontiers in …, 2020 - frontiersin.org
The epithelial-mesenchymal transition (EMT) represents a biological program during which
epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is …

Photoacoustic imaging in oncology: translational preclinical and early clinical experience

KS Valluru, KE Wilson, JK Willmann - Radiology, 2016 - pubs.rsna.org
Photoacoustic imaging has evolved into a clinically translatable platform with the potential to
complement existing imaging techniques for the management of cancer, including detection …

CD63+ Cancer‐Associated Fibroblasts Confer Tamoxifen Resistance to Breast Cancer Cells through Exosomal miR‐22

Y Gao, X Li, C Zeng, C Liu, Q Hao, W Li… - Advanced …, 2020 - Wiley Online Library
Tamoxifen remains the most effective treatment for estrogen receptor α (ERα)‐positive
breast cancer. However, many patients still develop resistance to tamoxifen in association …

Co9Se8 Nanoplates as a New Theranostic Platform for Photoacoustic/Magnetic Resonance Dual‐Modal‐Imaging‐Guided Chemo‐Photothermal Combination …

XR Song, X Wang, SX Yu, J Cao, SH Li, J Li… - Advanced …, 2015 - Wiley Online Library
DOI: 10.1002/adma. 201405634 for theranostic applications, including reduced
graphene,[10] transition metal dichalcogenides (TMDCs),[11] and topological insulators.[12] …

CDCP1 drives triple-negative breast cancer metastasis through reduction of lipid-droplet abundance and stimulation of fatty acid oxidation

HJ Wright, J Hou, B Xu, M Cortez, EO Potma… - Proceedings of the …, 2017 - pnas.org
Triple-negative breast cancer (TNBC) is notoriously aggressive with high metastatic
potential, which has recently been linked to high rates of fatty acid oxidation (FAO). Here we …

[HTML][HTML] Targeting long chain acyl-CoA synthetases for cancer therapy

M Rossi Sebastiano, G Konstantinidou - International journal of molecular …, 2019 - mdpi.com
The deregulation of cancer cell metabolic networks is now recognized as one of the
hallmarks of cancer. Abnormal lipid synthesis and extracellular lipid uptake are …

Prediction of tumor recurrence and therapy monitoring using ultrasound-guided photoacoustic imaging

S Mallidi, K Watanabe, D Timerman… - …, 2015 - pmc.ncbi.nlm.nih.gov
Selection and design of individualized treatments remains a key goal in cancer therapeutics;
prediction of response and tumor recurrence following a given therapy provides a basis for …

Clinical photoacoustic imaging of cancer

KS Valluru, JK Willmann - Ultrasonography, 2016 - pmc.ncbi.nlm.nih.gov
Photoacoustic imaging is a hybrid technique that shines laser light on tissue and measures
optically induced ultrasound signal. There is growing interest in the clinical community over …

Photoacoustic imaging as a tool to probe the tumour microenvironment

E Brown, J Brunker… - Disease models & …, 2019 - journals.biologists.com
The tumour microenvironment (TME) is a complex cellular ecosystem subjected to chemical
and physical signals that play a role in sha** tumour heterogeneity, invasion and …

Oxygen enhanced optoacoustic tomography (OE-OT) reveals vascular dynamics in murine models of prostate cancer

MR Tomaszewski, IQ Gonzalez, JPB O'Connor… - …, 2017 - pmc.ncbi.nlm.nih.gov
Poor oxygenation of solid tumours has been linked with resistance to chemo-and radio-
therapy and poor patient outcomes, hence non-invasive imaging of oxygen supply and …