[HTML][HTML] Monoclonal antibodies as an antibacterial approach against bacterial pathogens

DV Zurawski, MK McLendon - Antibiotics, 2020 - mdpi.com
In the beginning of the 21st century, the frequency of antimicrobial resistance (AMR) has
reached an apex, where even 4th and 5th generation antibiotics are becoming useless in …

Monoclonal antibody-based therapies for bacterial infections

MP Motley, K Banerjee, BC Fries - Current opinion in infectious …, 2019 - journals.lww.com
Despite the hurdles of identifying effective targets and understanding how mAbs provide
protection within different infections, we show that the progress made in these fields is a …

Anti-bacterial monoclonal antibodies: next generation therapy against superbugs

H Wang, D Chen, H Lu - Applied Microbiology and Biotechnology, 2022 - Springer
Prior to the nineteenth century, infectious disease was one of the leading causes of death.
Human life expectancy has roughly doubled over the past century as a result of the …

A natural human monoclonal antibody targeting Staphylococcus Protein A protects against Staphylococcus aureus bacteremia

AK Varshney, GA Kuzmicheva, J Lin, KM Sunley… - PloS one, 2018 - journals.plos.org
Staphylococcus aureus can cause devastating and life-threatening infections. With the
increase in multidrug resistant strains, novel therapies are needed. Limited success with …

[HTML][HTML] Multiplex detection of 24 staphylococcal enterotoxins in culture supernatant using liquid chromatography coupled to high-resolution mass spectrometry

D Lefebvre, K Blanco-Valle, JA Hennekinne, S Simon… - Toxins, 2022 - mdpi.com
Staphylococcal food poisoning outbreaks are caused by the ingestion of food contaminated
with staphylococcal enterotoxins (SEs). Among the 27 SEs described in the literature to date …

Phenolic compounds as natural microbial toxin detoxifying agents

B Saricaoglu, BG Subaşı, F Karbancioglu-Guler… - Toxicon, 2023 - Elsevier
Despite the abundance of promising studies, developments, and improvements about the
elimination of microbial toxins from food matrices, they are still considered as one of the …

Prevalence and Characterization of Staphylococcus aureus Isolated From Women and Children in Guangzhou, China

B Liang, J Mai, Y Liu, Y Huang, H Zhong, Y **e… - Frontiers in …, 2018 - frontiersin.org
The prevalent Staphylococcus aureus clones and antibiotic susceptibility profiles are known
to change dynamically and geographically; however, recent S. aureus strains causing …

Unraveling the Impact of Secreted Proteases on Hypervirulence in Staphylococcus aureus

BD Gimza, JK Jackson, AM Frey, BG Budny, D Chaput… - MBio, 2021 - journals.asm.org
Staphylococcus aureus controls the progression of infection through the coordinated
production of extracellular proteases, which selectively modulate virulence determinant …

[HTML][HTML] Epidemiological and Clinical Evidence for the Role of Toxins in S. aureus Human Disease

MR Bennett, IP Thomsen - Toxins, 2020 - mdpi.com
Staphylococcus aureus asymptomatically colonizes approximately 30–50% of the
population and is a leading cause of bacteremia, bone/joint infections, and skin infections in …

[HTML][HTML] Monoclonal antibodies targeting surface-exposed and secreted proteins from staphylococci

P Speziale, G Pietrocola - Vaccines, 2021 - mdpi.com
Staphylococci (specifically Staphylococcus aureus and Staphylococcus epidermidis) are the
causative agents of diseases ranging from superficial skin and soft tissue infections to …