The LOD paradox: when lower isn't always better in biosensor research and development

H Moulahoum, F Ghorbanizamani - Biosensors and Bioelectronics, 2024 - Elsevier
Biosensor research has long focused on achieving the lowest possible Limits of Detection
(LOD), driving significant advances in sensitivity and opening up new possibilities in …

Nanotechnology for cardiovascular diseases

Q Hu, Z Fang, J Ge, H Li - The Innovation, 2022 - cell.com
Cardiovascular diseases have become the major killers in today's world, among which
coronary artery diseases (CADs) make the greatest contributions to morbidity and mortality …

Nanotechnology-assisted microfluidic systems for chemical sensing, biosensing, and bioanalysis

Z Fattahi, M Hasanzadeh - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Microfluidics technology holds a special place in the field of biomedical and analytical
chemistry thanks to its properties, such as low consumption of reagent, quick analysis time …

Integrating potential-resolved electrochemiluminescence with molecularly imprinting immunoassay for simultaneous detection of dual acute myocardial infarction …

S He, P Zhang, J Sun, Y Ji, C Huang, N Jia - Biosensors and Bioelectronics, 2022 - Elsevier
A novel potential-resolved molecularly imprinted electrochemical luminescence (ECL)
immunosensor has been developed for the first time for the dual sensitive detection of …

Voltammetric biosensors for analytical detection of cardiac troponin biomarkers in acute myocardial infarction

A Pourali, MR Rashidi, J Barar, G Pavon-Djavid… - TrAC Trends in …, 2021 - Elsevier
The fast and precise diagnosis of acute myocardial infarction (AMI) is of great importance for
the survival of patients. Here, we provide key insights into the recent progress in …

Recent advances of electrochemical and optical biosensors for detection of C-reactive protein as a major inflammatory biomarker

H Sohrabi, H kholafazad Kordasht… - Microchemical …, 2020 - Elsevier
Early detection of inflammatory mediators including C-reactive protein (CRP) is of great
diagnostic importance in many human diseases. CRP elevates very fast in conditions such …

Progress, opportunities, and challenges of troponin analysis in the early diagnosis of cardiovascular diseases

X Du, X Su, W Zhang, S Yi, G Zhang, S Jiang… - Analytical …, 2021 - ACS Publications
Cardiovascular diseases (CVD) have one of the leading mortalities throughout the world; an
estimated 17.9 million people died from CVD in 2019, representing 32% of all global deaths …

A dry chemistry-based ultrasensitive electrochemiluminescence immunosensor for sample-to-answer detection of Cardiac Troponin I

T Zhan, Y Su, W Lai, Z Chen, C Zhang - Biosensors and Bioelectronics, 2022 - Elsevier
Dry chemistry-based fluorescence or colorimetric immunosensors have been widely applied
for point-of-care testing (POCT). However, dry chemistry-based electrochemiluminescence …

Enzyme-free electrochemical nano-immunosensor based on graphene quantum dots and gold nanoparticles for cardiac biomarker determination

BD Mansuriya, Z Altintas - Nanomaterials, 2021 - mdpi.com
An ultrasensitive enzyme-free electrochemical nano-immunosensor based on a screen-
printed gold electrode (SPGE) modified with graphene quantum dots (GQDs) and gold …

Construction of a desirable hyperbolic microfluidic chip for ultrasensitive determination of PCT based on chemiluminescence

B Yin, W Yue, ASMMF Sohan, X Wan, T Zhou… - Journal of Materials …, 2023 - pubs.rsc.org
Since procalcitonin (PCT) is a specific inflammation indicator of severe bacterial
inflammation and fungal infection, it is of great significance to construct a sensitive and rapid …