Emerging role of exosomes in cancer progression and tumor microenvironment remodeling
Cancer is one of the leading causes of death worldwide, and the factors responsible for its
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …
The hypoxia-driven crosstalk between tumor and tumor-associated macrophages: mechanisms and clinical treatment strategies
R Bai, Y Li, L Jian, Y Yang, L Zhao, M Wei - Molecular Cancer, 2022 - Springer
Given that hypoxia is a persistent physiological feature of many different solid tumors and a
key driver for cancer malignancy, it is thought to be a major target in cancer treatment …
key driver for cancer malignancy, it is thought to be a major target in cancer treatment …
Hypoxia induced changes of exosome cargo and subsequent biological effects
H Jiang, H Zhao, M Zhang, Y He, X Li, Y Xu… - Frontiers in …, 2022 - frontiersin.org
Exosomes are small extracellular vesicles that are secreted by almost all types of cells and
exist in almost all extracellular spaces. As an important mediator of intercellular …
exist in almost all extracellular spaces. As an important mediator of intercellular …
Exosomes: a new pathway for cancer drug resistance
Y Zhong, H Li, P Li, Y Chen, M Zhang, Z Yuan… - Frontiers in …, 2021 - frontiersin.org
Exosomes are extracellular vesicles (EVs) that are secreted into body fluids by multiple cell
types and are enriched in bioactive molecules, although their exact contents depend on the …
types and are enriched in bioactive molecules, although their exact contents depend on the …
Tumor-derived small extracellular vesicles: potential roles and mechanism in glioma
X Guo, R Sui, H Piao - Journal of Nanobiotechnology, 2022 - Springer
Small extracellular vesicles (SEVs) are extracellular vesicles containing DNA, RNA, and
proteins and are involved in intercellular communication and function, playing an essential …
proteins and are involved in intercellular communication and function, playing an essential …
Crucial role of the transcription factors family activator protein 2 in cancer: current clue and views
C **, Y Luo, Z Liang, X Li, D Kołat, L Zhao… - Journal of Translational …, 2023 - Springer
The transcription factor family activator protein 2 (TFAP2) is vital for regulating both
embryonic and oncogenic development. The TFAP2 family consists of five DNA-binding …
embryonic and oncogenic development. The TFAP2 family consists of five DNA-binding …
A review on the role of miR-1246 in the pathoetiology of different cancers
miR-1246 is a microRNA firstly recognized through application of a high throughput
sequencing technique in human embryonic stem cells. Subsequent studies have shown the …
sequencing technique in human embryonic stem cells. Subsequent studies have shown the …
Hypoxic glioma‐derived extracellular vesicles harboring MicroRNA‐10b‐5p enhance M2 polarization of macrophages to promote the development of glioma
B Li, C Yang, Z Zhu, H Chen, B Qi - CNS Neuroscience & …, 2022 - Wiley Online Library
Introduction The delivery of biomolecules by tumor cell‐secreted extracellular vesicles (EVs)
is linked to the development of glioma. Here, the present study was implemented to explore …
is linked to the development of glioma. Here, the present study was implemented to explore …
Hypoxia-driven changes in tumor microenvironment: Insights into exosome-mediated cell interactions
C Wang, S Xu, X Yang - International Journal of Nanomedicine, 2024 - Taylor & Francis
Hypoxia, as a prominent feature of the tumor microenvironment, has a profound impact on
the multicomponent changes within this environment. Under hypoxic conditions, the …
the multicomponent changes within this environment. Under hypoxic conditions, the …
Antifibrotic factor KLF4 is repressed by the miR-10/TFAP2A/TBX5 axis in dermal fibroblasts: insights from twins discordant for systemic sclerosis
M Malaab, L Renaud, N Takamura… - Annals of the …, 2022 - ard.bmj.com
Objectives Systemic sclerosis (SSc) is a complex disease of unknown aetiology in which
inflammation and fibrosis lead to multiple organ damage. There is currently no effective …
inflammation and fibrosis lead to multiple organ damage. There is currently no effective …