Motivation Despite the extensive manufacturing of antiviral drugs and vaccination, viral
infections continue to be a major human ailment. Antiviral peptides (AVPs) have emerged as …

Protein secondary structure prediction (PSSP) is a fundamental task in protein science and
computational biology, and it can be used to understand protein 3-dimensional (3-D) …

Accurately identifying the protein-ligand binding sites or pockets is of significant importance
for both protein function analysis and drug design. Although much progress has been made …

Protein-DNA interactions are ubiquitous in a wide variety of biological processes. Correctly
locating DNA-binding residues solely from protein sequences is an important but …

Correctly localizing the protein-ATP binding residues is valuable for both basic experimental
biology and drug discovery studies. Protein-ATP binding residues prediction is a typical …

Cell-penetrating peptides (CPPs) are special peptides capable of carrying a variety of
bioactive molecules, such as genetic materials, short interfering RNAs and nanoparticles …

Protein-protein interactions exist ubiquitously and play important roles in the life cycles of
living cells. The interaction sites (residues) are essential to understanding the underlying …

Accurate protein secondary structure prediction (PSSP) is essential to identify structural
classes, protein folds, and its tertiary structure. To identify the secondary structure …

We are facing an era with annotated biological data rapidly and continuously generated.
How to effectively incorporate new annotated data into the learning step is crucial for …

Metaheuristics have been employed in solving several optimization and NP-hard problems
owing to their ability to avoid local optima entrapment, flexibility and robustness, simplicity …