Adult neurogenesis and the dentate gyrus: predicting function from form
Hypotheses about the functional properties of the dentate gyrus and adult dentate
neurogenesis have been shaped by early observations of the anatomy of this region, mostly …
neurogenesis have been shaped by early observations of the anatomy of this region, mostly …
Pattern separation of spiketrains in hippocampal neurons
Pattern separation is a process that minimizes overlap between patterns of neuronal activity
representing similar experiences. Theoretical work suggests that the dentate gyrus (DG) …
representing similar experiences. Theoretical work suggests that the dentate gyrus (DG) …
Pattern separation in the hippocampus through the eyes of computational modeling
Pattern separation is a mnemonic process that has been extensively studied over the years.
It entails the ability‐of primarily hippocampal circuits‐to distinguish between highly similar …
It entails the ability‐of primarily hippocampal circuits‐to distinguish between highly similar …
Exercise-induced enhancement of synaptic function triggered by the inverse BAR protein, Mtss1L
Exercise is a potent enhancer of learning and memory, yet we know little of the underlying
mechanisms that likely include alterations in synaptic efficacy in the hippocampus. To …
mechanisms that likely include alterations in synaptic efficacy in the hippocampus. To …
Behavioral pattern separation and cognitive flexibility are enhanced in a mouse model of increased lateral entorhinal cortex-dentate gyrus circuit activity
Behavioral pattern separation and cognitive flexibility are essential cognitive abilities that
are disrupted in many brain disorders. A better understanding of the neural circuitry involved …
are disrupted in many brain disorders. A better understanding of the neural circuitry involved …
Disparate forms of heterogeneities and interactions among them drive channel decorrelation in the dentate gyrus: Degeneracy and dominance
The ability of a neuronal population to effectuate channel decorrelation, which is one form of
response decorrelation, has been identified as an essential prelude to efficient neural …
response decorrelation, has been identified as an essential prelude to efficient neural …
Deficits in behavioral and neuronal pattern separation in temporal lobe epilepsy
In temporal lobe epilepsy, the ability of the dentate gyrus to limit excitatory cortical input to
the hippocampus breaks down, leading to seizures. The dentate gyrus is also thought to …
the hippocampus breaks down, leading to seizures. The dentate gyrus is also thought to …
Quantitative properties of a feedback circuit predict frequency-dependent pattern separation
Feedback inhibitory motifs are thought to be important for pattern separation across species.
How feedback circuits may implement pattern separation of biologically plausible …
How feedback circuits may implement pattern separation of biologically plausible …
Sparse modern hopfield networks
Ramsauer et al.(2021) recently pointed out a connection between modern Hopfield
networks and attention heads in transformers. In this paper, we extend their framework to a …
networks and attention heads in transformers. In this paper, we extend their framework to a …
Modeling contextual modulation of memory associations in the hippocampus
We present a computational model of how memories can be contextually acquired and
recalled in the hippocampus. Our adaptive contextual memory model comprises the lateral …
recalled in the hippocampus. Our adaptive contextual memory model comprises the lateral …