Histone methyltransferase DOT1L maintains identity and restricts cytotoxic potential of CD8 T cells

M Malik, WJ de Leeuw, MA Aslam… - bioRxiv, 2025 - biorxiv.org
The histone methyltransferase DOT1L is emerging as a central epigenetic regulator in
immune cells. Loss of DOT1L during development of CD8 T cells in vivo leads to gain of …