Advances and utility of the human plasma proteome
The study of proteins circulating in blood offers tremendous opportunities to diagnose,
stratify, or possibly prevent diseases. With recent technological advances and the urgent …
stratify, or possibly prevent diseases. With recent technological advances and the urgent …
The nanoparticle biomolecule corona: lessons learned–challenge accepted?
D Docter, D Westmeier, M Markiewicz… - Chemical Society …, 2015 - pubs.rsc.org
Besides the wide use of engineered nanomaterials (NMs) in technical products, their
applications are not only increasing in biotechnology and biomedicine, but also in the …
applications are not only increasing in biotechnology and biomedicine, but also in the …
Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona
Large-scale, unbiased proteomics studies are constrained by the complexity of the plasma
proteome. Here we report a highly parallel protein quantitation platform integrating …
proteome. Here we report a highly parallel protein quantitation platform integrating …
The human secretome
The proteins secreted by human cells (collectively referred to as the secretome) are
important not only for the basic understanding of human biology but also for the identification …
important not only for the basic understanding of human biology but also for the identification …
[HTML][HTML] Neuronal activity promotes glioma growth through neuroligin-3 secretion
HS Venkatesh, TB Johung, V Caretti, A Noll, Y Tang… - Cell, 2015 - cell.com
Active neurons exert a mitogenic effect on normal neural precursor and oligodendroglial
precursor cells, the putative cellular origins of high-grade glioma (HGG). By using …
precursor cells, the putative cellular origins of high-grade glioma (HGG). By using …
The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways
JM Burkhart, M Vaudel, S Gambaryan… - Blood, The Journal …, 2012 - ashpublications.org
Antiplatelet treatment is of fundamental importance in combatting functions/dysfunction of
platelets in the pathogenesis of cardiovascular and inflammatory diseases. Dysfunction of …
platelets in the pathogenesis of cardiovascular and inflammatory diseases. Dysfunction of …
[HTML][HTML] Technical advances in proteomics: new developments in data-independent acquisition
The ultimate aim of proteomics is to fully identify and quantify the entire complement of
proteins and post-translational modifications in biological samples of interest. For the last 15 …
proteins and post-translational modifications in biological samples of interest. For the last 15 …
Nanoparticle size is a critical physicochemical determinant of the human blood plasma corona: a comprehensive quantitative proteomic analysis
S Tenzer, D Docter, S Rosfa, A Wlodarski, J Kuharev… - ACS …, 2011 - ACS Publications
In biological fluids, proteins associate with nanoparticles, leading to a protein “corona”
defining the biological identity of the particle. However, a comprehensive knowledge of …
defining the biological identity of the particle. However, a comprehensive knowledge of …
The human plasma proteome draft of 2017: building on the human plasma PeptideAtlas from mass spectrometry and complementary assays
Human blood plasma provides a highly accessible window to the proteome of any individual
in health and disease. Since its inception in 2002, the Human Proteome Organization's …
in health and disease. Since its inception in 2002, the Human Proteome Organization's …
Quantitative variability of 342 plasma proteins in a human twin population
The degree and the origins of quantitative variability of most human plasma proteins are
largely unknown. Because the twin study design provides a natural opportunity to estimate …
largely unknown. Because the twin study design provides a natural opportunity to estimate …