Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases
Mesenchymal stem cells (MSCs; also referred to as mesenchymal stromal cells) have
attracted much attention for their ability to regulate inflammatory processes. Their therapeutic …
attracted much attention for their ability to regulate inflammatory processes. Their therapeutic …
Mesenchymal stem cells in health and disease
Mesenchymal stem cells (MSCs) are a heterogeneous subset of stromal stem cells that can
be isolated from many adult tissues. They can differentiate into cells of the mesodermal …
be isolated from many adult tissues. They can differentiate into cells of the mesodermal …
Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study
Background Severe graft-versus-host disease (GVHD) is a life-threatening complication after
allogeneic transplantation with haemopoietic stem cells. Mesenchymal stem cells modulate …
allogeneic transplantation with haemopoietic stem cells. Mesenchymal stem cells modulate …
Gene therapy using haematopoietic stem and progenitor cells
Haematopoietic stem and progenitor cell (HSPC) gene therapy has emerged as an effective
treatment modality for monogenic disorders of the blood system such as primary …
treatment modality for monogenic disorders of the blood system such as primary …
Regenerative capacity of adipose derived stem cells (ADSCs), comparison with mesenchymal stem cells (MSCs)
L Mazini, L Rochette, M Amine, G Malka - International journal of …, 2019 - mdpi.com
Adipose tissue is now on the top one of stem cell sources regarding its accessibility,
abundance, and less painful collection procedure when compared to other sources. The …
abundance, and less painful collection procedure when compared to other sources. The …
Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study
M Duijvestein, ACW Vos, H Roelofs, ME Wildenberg… - Gut, 2010 - gut.bmj.com
Background and aim Mesenchymal stromal cells (MSCs) are pluripotent cells that have
immunosuppressive effects both in vitro and in experimental colitis. Promising results of …
immunosuppressive effects both in vitro and in experimental colitis. Promising results of …
MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin …
GM Spaggiari, H Abdelrazik… - Blood, The Journal of …, 2009 - ashpublications.org
Various studies analyzed the inhibitory effect exerted by mesenchymal stem cells (MSCs) on
cells of the innate or acquired immunity. Myeloid dendritic cells (DCs) are also susceptible to …
cells of the innate or acquired immunity. Myeloid dendritic cells (DCs) are also susceptible to …
Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease
R Ciccocioppo, ME Bernardo, A Sgarella, R Maccario… - Gut, 2011 - gut.bmj.com
Objective External fistulas represent a disabling manifestation of Crohn's disease with a
difficult curability and a high relapse rate despite a large therapeutic armamentarium. Stem …
difficult curability and a high relapse rate despite a large therapeutic armamentarium. Stem …
Adipose tissue-derived multipotent stromal cells have a higher immunomodulatory capacity than their bone marrow-derived counterparts
SM Melief, JJ Zwaginga, WE Fibbe… - Stem cells translational …, 2013 - academic.oup.com
Adipose tissue-derived multipotent stromal cells (AT-MSCs) are studied as an alternative to
bone marrow-derived multipotent stromal cells (BM-MSCs) for immunomodulatory treatment …
bone marrow-derived multipotent stromal cells (BM-MSCs) for immunomodulatory treatment …
Mesenchymal stem or stromal cells: a review of clinical applications and manufacturing practices
Mesenchymal stem cells (MSC s) have recently generated great interest in the fields of
regenerative medicine and immunotherapy due to their unique biologic properties. In this …
regenerative medicine and immunotherapy due to their unique biologic properties. In this …