Epidemiology of ovarian cancer: a review

BM Reid, JB Permuth, TA Sellers - Cancer biology & medicine, 2017 - cancerbiomed.org
Ovarian cancer (OC) is the seventh most commonly diagnosed cancer among women in the
world and the tenth most common in China. Epithelial OC is the most predominant …

[HTML][HTML] Epithelial ovarian cancer: providing evidence of predisposition genes

S Shah, A Cheung, M Kutka, M Sheriff… - International Journal of …, 2022 - mdpi.com
Epithelial ovarian cancer (EOC) is one of the cancers most influenced by hereditary factors.
A fourth to a fifth of unselected EOC patients carry pathogenic variants (PVs) in a number of …

Inherited mutations in women with ovarian carcinoma

BM Norquist, MI Harrell, MF Brady, T Walsh… - JAMA …, 2016 - jamanetwork.com
Importance Germline mutations inBRCA1andBRCA2are relatively common in women with
ovarian, fallopian tube, and peritoneal carcinoma (OC) causing a greatly increased lifetime …

Ovarian cancer

GC Jayson, EC Kohn, HC Kitchener, JA Ledermann - The lancet, 2014 - thelancet.com
Epithelial ovarian cancer is the commonest cause of gynaecological cancer-associated
death. The disease typically presents in postmenopausal women, with a few months of …

Mismatch repair deficiency and response to immune checkpoint blockade

V Lee, A Murphy, DT Le, LA Diaz Jr - The oncologist, 2016 - academic.oup.com
More than 1.6 million new cases of cancer will be diagnosed in the US in 2016, resulting in
more than 500,000 deaths. Although chemotherapy has been the mainstay of treatment in …

[HTML][HTML] Hereditary ovarian cancer: towards a cost-effective prevention strategy

A Ghose, A Bolina, I Mahajan, SA Raza… - International journal of …, 2022 - mdpi.com
Ovarian cancer (OC) is the most lethal gynaecological malignancy. The search for a widely
affordable and accessible screening strategy to reduce mortality from OC is still ongoing …

[HTML][HTML] Ovarian cancer in Lynch syndrome; a systematic review

JM Helder-Woolderink, EA Blok, HFA Vasen… - European Journal of …, 2016 - Elsevier
Objective The aim was to systematically review the characteristics of ovarian cancer in
women with Lynch syndrome (LS) and evaluate the role of surveillance in detection of …

The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population

H Song, MS Cicek, E Dicks, P Harrington… - Human molecular …, 2014 - academic.oup.com
The aim of this study was to estimate the contribution of deleterious mutations in BRCA1,
BRCA2, MLH1, MSH2, MSH6 and PMS2 to invasive epithelial ovarian cancer (EOC) in the …

Genetic epidemiology of ovarian cancer and prospects for polygenic risk prediction

MR Jones, D Kamara, BY Karlan, PDP Pharoah… - Gynecologic …, 2017 - Elsevier
Epithelial ovarian cancer (EOC) is a heterogeneous disease with a major heritable
component. The different histotypes of invasive disease–high grade serous, clear cell …