Royal jelly: biological action and health benefits

N Oršolić, M Jazvinšćak Jembrek - International journal of molecular …, 2024 - mdpi.com
Royal jelly (RJ) is a highly nutritious natural product with great potential for use in medicine,
cosmetics, and as a health-promoting food. This bee product is a mixture of important …

Cadmium as a testicular toxicant: A Review

JK Bhardwaj, H Panchal, P Saraf - Journal of Applied …, 2021 - Wiley Online Library
Cadmium (Cd) is a toxic heavy metal with no known biological functions in the human body.
Due to a considerably long biological half‐life and very low rate of excretion, accumulation …

Protocatechuic acid mitigates cadmium-induced neurotoxicity in rats: Role of oxidative stress, inflammation and apoptosis

EM Al Olayan, AS Aloufi, OD AlAmri, H Ola… - Science of the total …, 2020 - Elsevier
Environmental and occupational exposure to heavy metals, including cadmium (Cd), is
associated with extremely adverse impacts to living systems. Antioxidant agents are …

The role of toxic metals and metalloids in Nrf2 signaling

A Buha, K Baralić, D Djukic-Cosic, Z Bulat, A Tinkov… - Antioxidants, 2021 - mdpi.com
Nuclear factor erythroid 2-related factor 2 (Nrf2), an emerging regulator of cellular resistance
to oxidants, serves as one of the key defensive factors against a range of pathological …

Diacerein downregulates NLRP3/Caspase-1/IL-1β and IL-6/STAT3 pathways of inflammation and apoptosis in a rat model of cadmium testicular toxicity

AA Fouad, AM Abdel-Aziz, AAH Hamouda - Biological Trace Element …, 2020 - Springer
The potential gonadal protective effect of diacerein (DCN) and its underlying mechanisms
were studied in a rat model of cadmium-induced testicular toxicity. The rats received DCN …

Efficacy of propolis and royal jelly in attenuating cadmium-induced spermatogenesis and steroidogenesis dysregulation, causing infertility in rats

A Amr, AEA Karim, M Augustyniak, AE Wakil… - … Science and Pollution …, 2024 - Springer
Bee-derived pharmaceutical products, including propolis (PRO) and royal jelly (ROJ),
possess outstanding pharmacological properties. However, their efficiency in counteracting …

Cyanidin-3-O-glucoside restores spermatogenic dysfunction in cadmium-exposed pubertal mice via histone ubiquitination and mitigating oxidative damage

X Li, Z Yao, D Yang, X Jiang, J Sun, L Tian, J Hu… - Journal of Hazardous …, 2020 - Elsevier
Cadmium (Cd) is an environmental contaminant found in soil, water, and food, and can
cause oxidative stress and male reproductive damage. During puberty, the male …

Discovery of a potent glutathione peroxidase 4 inhibitor as a selective ferroptosis inducer

C Xu, Z **ao, J Wang, H Lai, T Zhang… - Journal of Medicinal …, 2021 - ACS Publications
Potent and selective ferroptosis regulators promote an intensive understanding of the
regulation and mechanisms underlying ferroptosis, which is highly associated with various …

Ferulic acid influences Nrf2 activation to restore testicular tissue from cadmium‐induced oxidative challenge, inflammation, and apoptosis in rats

RB Kassab, MS Lokman, HMA Daabo… - Journal of food …, 2020 - Wiley Online Library
Here, we examined the protective effect of ferulic acid (FA) on cadmium chloride (CdCl2)‐
mediated reproductive toxicity in male rats. Animals were divided into four groups: control …

m6A-methylated Lonp1 drives mitochondrial proteostasis stress to induce testicular pyroptosis upon environmental cadmium exposure

KW Ouyang, TT Wang, H Wang, YX Luo, YF Hu… - Science of The Total …, 2024 - Elsevier
Cadmium (Cd) is a widely distributed typical environmental pollutant and one of the most
toxic heavy metals. It is well-known that environmental Cd causes testicular damage by …