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[HTML][HTML] Organs-on-chips technologies–A guide from disease models to opportunities for drug development
Current in-vitro 2D cultures and animal models present severe limitations in recapitulating
human physiopathology with striking discrepancies in estimating drug efficacy and side …
human physiopathology with striking discrepancies in estimating drug efficacy and side …
Musculoskeletal Organs‐on‐Chips: An Emerging Platform for Studying the Nanotechnology–Biology Interface
Nanotechnology‐based approaches are promising for the treatment of musculoskeletal
(MSK) disorders, which present significant clinical burdens and challenges, but their clinical …
(MSK) disorders, which present significant clinical burdens and challenges, but their clinical …
Sensitive and specific CRISPR-Cas12a assisted nanopore with RPA for Monkeypox detection
Monkeypox virus (MPXV) poses a global health emergency, necessitating rapid, simple, and
accurate detection to manage its spread effectively. The Clustered Regularly Interspaced …
accurate detection to manage its spread effectively. The Clustered Regularly Interspaced …
Advances in TEER measurements of biological barriers in microphysiological systems
Biological barriers are multicellular structures that precisely regulate the transport of ions,
biomolecules, drugs, cells, and other organisms. Transendothelial/epithelial electrical …
biomolecules, drugs, cells, and other organisms. Transendothelial/epithelial electrical …
Revolutionizing drug development: harnessing the potential of organ-on-chip technology for disease modeling and drug discovery
The inefficiency of existing animal models to precisely predict human pharmacological
effects is the root reason for drug development failure. Microphysiological system/organ-on …
effects is the root reason for drug development failure. Microphysiological system/organ-on …
[HTML][HTML] Microfluidic organ-on-a-chip devices for liver disease modeling in vitro
P Kanabekova, A Kadyrova, G Kulsharova - Micromachines, 2022 - mdpi.com
Mortality from liver disease conditions continues to be very high. As liver diseases manifest
and progress silently, prompt measures after diagnosis are essential in the treatment of …
and progress silently, prompt measures after diagnosis are essential in the treatment of …
Organ-on-a-chip platforms integrated with biosensors for precise monitoring of the cells and cellular microenvironment
W Yang, T Li, S Liao, J Zhou, L Huang - TrAC Trends in Analytical …, 2024 - Elsevier
Abstract Organs-on-chips (OoCs) are in vitro models that simulate the anatomical and
physiological structure of human organs at the micro-scale level. With the advantages of …
physiological structure of human organs at the micro-scale level. With the advantages of …
Recent advances in Organ-on-a-Chip models: How precision engineering integrates cutting edge technologies in fabrication and characterization
There is an increasing need for better preclinical therapeutic development models suitable
for the human body. As a result, there has been a shift from traditional animal models to …
for the human body. As a result, there has been a shift from traditional animal models to …
[HTML][HTML] Algae-derived bioactive compounds as potential pharmaceuticals for cancer therapy: A comprehensive review
Cancer is considered a pandemic, costing precious lives throughout the globe. Besides its
deadly outcomes, the survival rate after cancer therapies is meager. Anti-cancer drug …
deadly outcomes, the survival rate after cancer therapies is meager. Anti-cancer drug …
High performance inkjet printed embedded electrochemical sensors for monitoring hypoxia in a gut bilayer microfluidic chip
Sensing devices have shown tremendous potential for monitoring state-of-the-art organ chip
devices. However, challenges like miniaturization while maintaining higher performance …
devices. However, challenges like miniaturization while maintaining higher performance …