Drugging the efferocytosis process: concepts and opportunities
The daily removal of billions of apoptotic cells in the human body via the process of
efferocytosis is essential for homeostasis. To allow for this continuous efferocytosis, rapid …
efferocytosis is essential for homeostasis. To allow for this continuous efferocytosis, rapid …
Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?
SE Engelen, AJB Robinson, YX Zurke… - Nature Reviews …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis
Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …
and contribute to the development of novel diagnostic and therapeutic strategies to further …
Targeting inflammation in atherosclerosis—from experimental insights to the clinic
Atherosclerosis, a dominant and growing cause of death and disability worldwide, involves
inflammation from its inception to the emergence of complications. Targeting inflammatory …
inflammation from its inception to the emergence of complications. Targeting inflammatory …
Shedding light on extracellular vesicle biogenesis and bioengineering
F Teng, M Fussenegger - Advanced Science, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are biocompatible, nano‐sized secreted vesicles containing
many types of biomolecules, including proteins, RNAs, DNAs, lipids, and metabolites. Their …
many types of biomolecules, including proteins, RNAs, DNAs, lipids, and metabolites. Their …
Tailoring materials for modulation of macrophage fate
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
Targeting the microenvironment of vulnerable atherosclerotic plaques: an emerging diagnosis and therapy strategy for atherosclerosis
Atherosclerosis is considered one of the primary causes of cardiovascular diseases (CVDs).
Unpredictable rupture of the vulnerable atherosclerotic plaques triggers adverse …
Unpredictable rupture of the vulnerable atherosclerotic plaques triggers adverse …
Dysfunctional vascular endothelium as a driver of atherosclerosis: emerging insights into pathogenesis and treatment
Atherosclerosis, the chronic accumulation of cholesterol-rich plaque within arteries, is
associated with a broad spectrum of cardiovascular diseases including myocardial …
associated with a broad spectrum of cardiovascular diseases including myocardial …
Nanotechnology for modern medicine: next step towards clinical translation
The field of nanotechnology has been a significant research focus in the last thirty years.
This emphasis is due to the unique optical, electrical, magnetic, chemical and biological …
This emphasis is due to the unique optical, electrical, magnetic, chemical and biological …
Small molecule-assisted assembly of multifunctional ceria nanozymes for synergistic treatment of atherosclerosis
X Fu, X Yu, J Jiang, J Yang, L Chen, Z Yang… - Nature …, 2022 - nature.com
Considering that intravascular reactive oxygen species (ROS) and inflammation are two
characteristic features of the atherosclerotic microenvironment, develo** an appropriate …
characteristic features of the atherosclerotic microenvironment, develo** an appropriate …