Emerging therapies for hepatocellular carcinoma (HCC)

E Chakraborty, D Sarkar - Cancers, 2022‏ - mdpi.com
Simple Summary Primary liver cancer, also known as Hepatocellular carcinoma (HCC), is
considered to be a major global health challenge. Due to delays in diagnosis at early …

Nanomaterials-based photosensitizers and delivery systems for photodynamic cancer therapy

XT Yu, SY Sui, YX He, CH Yu, Q Peng - Biomaterials advances, 2022‏ - Elsevier
The increasing cancer morbidity and mortality requires the development of high-efficiency
and low-toxicity anticancer approaches. In recent years, photodynamic therapy (PDT) has …

Hypericin: A natural anthraquinone as promising therapeutic agent

JJ Wu, J Zhang, CY **a, K Ding, XX Li, XG Pan, JK Xu… - Phytomedicine, 2023‏ - Elsevier
Background: Hypericin is a prominent secondary metabolite mainly existing in genus
Hypericum. It has become a research focus for a quiet long time owing to its extensively …

Understanding the nanostructures of prolamin-based oral carrier to deliver functional compounds: A review

X Chen, ZX Wang, W Liu, YC Wu, HJ Li - Trends in Food Science & …, 2024‏ - Elsevier
Background The high hydrophobicity of prolamin results in the mucoadhesive properties,
enabling it suitable for oral delivery. Prolamin could self-assemble into nanospheres for a …

[HTML][HTML] Enhancing antifungal treatment of Candida albicans with hypericin-loaded nanostructured lipid carriers in hydrogels: characterization, in vitro, and in vivo …

MR Sato, JA Oshiro-Junior, CF Rodero, FI Boni… - Pharmaceuticals, 2023‏ - mdpi.com
Background: Vulvovaginal candidiasis (VVC) is a worldwide public health problem caused
predominantly by the opportunistic polymorphic fungus Candida albicans, whose …

Improved anticancer efficacy of methyl pyropheophorbide-a–incorporated solid lipid nanoparticles in photodynamic therapy

S Yeo, TH Lee, MJ Kim, YK Shim, I Yoon, YK Song… - Scientific Reports, 2023‏ - nature.com
Photodynamic therapy (PDT) is a promising anticancer treatment because it is patient-
friendly and non-invasive. Methyl pyropheophorbide-a (MPPa), one of the chlorin class …

Tumor-targeted delivery of honokiol via polysialic acid modified zein nanoparticles prevents breast cancer progression and metastasis

Q Zhang, D Li, S Guan, D Liu, J Wang, G **ng… - International Journal of …, 2022‏ - Elsevier
In this work, we developed polysialic acid (PSA) modified zein nanoparticles for targeted
delivery of honokiol (HNK) to enhance drug delivery efficiency and specific biodistribution at …

Photoactive Parietin-loaded nanocarriers as an efficient therapeutic platform against triple-negative breast cancer

AM Ayoub, MS Atya, AM Abdelsalam, J Schulze… - International journal of …, 2023‏ - Elsevier
The application of photodynamic therapy has become more and more important in
combating cancer. However, the high lipophilic nature of most photosensitizers limits their …

[HTML][HTML] Recent innovations of mesoporous silica nanoparticles combined with photodynamic therapy for improving cancer treatment

DS Nady, A Hassan, MU Amin, U Bakowsky, SA Fahmy - Pharmaceutics, 2023‏ - mdpi.com
Cancer is a global health burden and is one of the leading causes of death. Photodynamic
therapy (PDT) is considered an alternative approach to conventional cancer treatment. PDT …

Parietin cyclodextrin-inclusion complex as an effective formulation for bacterial photoinactivation

AM Ayoub, B Gutberlet, E Preis, AM Abdelsalam… - Pharmaceutics, 2022‏ - mdpi.com
Multidrug resistance in pathogenic bacteria has become a significant public health concern.
As an alternative therapeutic option, antimicrobial photodynamic therapy (aPDT) can …