Synthetic dynamic helical polymers (supramolecular and covalent) and foldamers share the
helix as a structural motif. Although the materials are different, these systems also share …

The membrane proteins found in nature control many important cellular functions, including
signal transduction and transmembrane ion transport, and these, in turn, are regulated by …

Lipid bilayer membranes form compartments requisite for life. Interfacing supramolecular
systems, including receptors, catalysts, signal transducers and ion transporters, enables the …

Signal transduction across biological membranes enables cells to detect and respond to
diverse chemical or physical signals, and replicating these complex biological processes …

Living cells possess a variety of transmembrane signaling systems that receive chemical
and physical cues from the environment and transduce this information into an intracellular …

Figure 73: The proposed catalyst/substrate interaction shown in Figure 73 corresponds to
the related sulfoxidation catalyzed by chiral phosphoric acid PA 5 (ref 133). Please note that …

Foldamers can be made more than pieces of static, conformationally uniform molecular
architecture by designing into their structure the conformational dynamism characteristic of …

Molecular biology achieves control over complex reaction networks by means of molecular
systems that translate a chemical input (such as ligand binding) into an orthogonal chemical …

Signal transduction through G-protein-coupled receptors (GPCRs) involves binding to
signalling molecules at the cell surface, which leads to global changes in molecular …

Biological systems have evolved a number of different strategies to communicate
information on the molecular scale. Among these, the propagation of conformational change …