Redox homeostasis is a delicate balancing act of maintaining appropriate levels of
antioxidant defense mechanisms and reactive oxidizing oxygen and nitrogen species. Any …

Extensive research during the past three decades has demonstrated the mechanisms by
which an imbalance in the redox status of prooxidant/antioxidant reactions in cells with …

Keratoconus (KC) is a progressive corneal ecstasia characterized by thinning and
weakening of the cornea that leads to a cone-like appearance, scarring, and decreased …

Dry eye disease (DED) is a multifactorial syndrome that can be caused by alteration in the
quality or quantity of the precorneal tear film. It is considered one of the most common ocular …

Abstract" The Diseases of the Horny-coat of The Eye", known today as keratoconus, is a
progressive, multifactorial, non-inflammatory ectatic corneal disorder that is characterized by …

Keratoconus (KC) is a progressive corneal degeneration characterized by structural
changes consisting of progressive thinning and steepening of the cornea. These alterations …

Collagen crosslinking provides the mechanical strength required for physiological
maintenance of the extracellular matrix in most tissues in the human body, including the …

Metabolomics is the study of endogenous and exogenous metabolites in biological systems,
which aims to provide comparative semi-quantitative information about all metabolites in the …

Compared to the other classes of glycosaminoglycans (GAG s), that is, chondroitin/dermatan
sulfate, heparin/heparan sulfate and hyaluronan, keratan sulfate (KS), have the least known …

Keratoconus (KC) is a corneal ectatic condition characterized by focal structural changes,
resulting in progressive thinning, biomechanical weakening, and stee** of the cornea that …