Tuberculous meningitis

RJ Wilkinson, U Rohlwink, UK Misra… - Nature reviews …, 2017 - nature.com
Tuberculosis remains a global health problem, with an estimated 10.4 million cases and 1.8
million deaths resulting from the disease in 2015. The most lethal and disabling form of …

The pathogenesis of tuberculous meningitis

AG Davis, UK Rohlwink, A Proust… - Journal of leukocyte …, 2019 - academic.oup.com
Tuberculosis (TB) remains a leading cause of death globally. Dissemination of TB to the
brain results in the most severe form of extrapulmonary TB, tuberculous meningitis (TBM) …

Tuberculous meningitis in children: Clinical management & outcome

BD Daniel, GA Grace, M Natrajan - Indian Journal of Medical …, 2019 - journals.lww.com
Although the occurrence of tuberculous meningitis (TBM) in children is relatively rare, but it
is associated with higher rates of mortality and severe morbidity. The peak incidence of TBM …

Bacterial meningitis in Africa

T Barichello, CH Rocha Catalão, UK Rohlwink… - Frontiers in …, 2023 - frontiersin.org
Bacterial meningitis differs globally, and the incidence and case fatality rates vary by region,
country, pathogen, and age group; being a life-threatening disease with a high case fatality …

Biomarkers of cerebral injury and inflammation in pediatric tuberculous meningitis

UK Rohlwink, K Mauff, KA Wilkinson… - Clinical Infectious …, 2017 - academic.oup.com
Background Tuberculous meningitis (TBM) leads to death or disability in half the affected
individuals. Tools to assess severity and predict outcome are lacking. Neurospecific …

Tuberculous meningitis in children and adults: new insights for an ancient foe

A Mezochow, K Thakur, C Vinnard - Current neurology and neuroscience …, 2017 - Springer
Abstract Purpose of Review Tuberculous meningitis is the most devastating manifestation of
infection with Mycobacterium tuberculosis and represents a medical emergency …

Global frequency and clinical features of stroke in patients with tuberculous meningitis: a systematic review

MCC Sy, AI Espiritu, JLR Pascual - JAMA network open, 2022 - jamanetwork.com
Importance Stroke in tuberculous meningitis (TBM) is associated with significant morbidity
and mortality. Objective To determine the country-specific, regional, and overall prevalence …

[HTML][HTML] Microglia activation in a pediatric rabbit model of tuberculous meningitis

EW Tucker, S Pokkali, Z Zhang… - Disease models & …, 2016 - journals.biologists.com
Central nervous system (CNS) tuberculosis (TB) is the most severe form of extra-pulmonary
TB and disproportionately affects young children where the develo** brain has a unique …

Tuberculous meningitis: a roadmap for advancing basic and translational research

SK Jain, DM Tobin, EW Tucker, V Venketaraman… - Nature …, 2018 - nature.com
Tuberculous meningitis is a serious, life-threatening disease affecting vulnerable
populations, including HIV-infected individuals and young children. The US National …

Imaging recommendations and algorithms for pediatric tuberculosis: part 2—extrathoracic tuberculosis

BF Laya, NDP Concepcion, S Andronikou… - Pediatric …, 2023 - Springer
Despite advances in diagnosis and treatment in recent years, tuberculosis (TB) remains a
global health concern. Children are amongst the most vulnerable groups affected by this …