Sleep and anxiety: From mechanisms to interventions
SL Chellappa, D Aeschbach - Sleep medicine reviews, 2022 - Elsevier
Anxiety is the most common mental health problem worldwide. Epidemiological studies
show that sleep disturbances, particularly insomnia, affect∼ 50% of individuals with anxiety …
show that sleep disturbances, particularly insomnia, affect∼ 50% of individuals with anxiety …
Animal models of PTSD: a challenge to be met
G Richter-Levin, O Stork, MV Schmidt - Molecular psychiatry, 2019 - nature.com
Recent years have seen increased interest in psychopathologies related to trauma
exposure. Specifically, there has been a growing awareness to posttraumatic stress disorder …
exposure. Specifically, there has been a growing awareness to posttraumatic stress disorder …
Transcriptomic organization of the human brain in post-traumatic stress disorder
Despite extensive study of the neurobiological correlates of post-traumatic stress disorder
(PTSD), little is known about its molecular determinants. Here, differential gene expression …
(PTSD), little is known about its molecular determinants. Here, differential gene expression …
PTSD-related neuroimaging abnormalities in brain function, structure, and biochemistry
Although approximately 90% of the US population will experience a traumatic event within
their lifetime, only a fraction of those traumatized individuals will develop posttraumatic …
their lifetime, only a fraction of those traumatized individuals will develop posttraumatic …
Understanding the molecular mechanisms underpinning gene by environment interactions in psychiatric disorders: the FKBP5 model
Epidemiologic and genetic studies suggest common environmental and genetic risk factors
for a number of psychiatric disorders, including depression, bipolar disorder, and …
for a number of psychiatric disorders, including depression, bipolar disorder, and …
PTSD is associated with neuroimmune suppression: evidence from PET imaging and postmortem transcriptomic studies
Despite well-known peripheral immune activation in posttraumatic stress disorder (PTSD),
there are no studies of brain immunologic regulation in individuals with PTSD.[11C] PBR28 …
there are no studies of brain immunologic regulation in individuals with PTSD.[11C] PBR28 …
Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex
Identification and characterisation of novel targets for treatment is a priority in the field of
psychiatry. FKBP5 is a gene with decades of evidence suggesting its pathogenic role in a …
psychiatry. FKBP5 is a gene with decades of evidence suggesting its pathogenic role in a …
Functional and structural brain abnormalities in posttraumatic stress disorder: A multimodal meta-analysis of neuroimaging studies
Background Numerous resting-state functional and structural studies have revealed that
many brain regions are involved in the pathogenesis of posttraumatic stress disorder …
many brain regions are involved in the pathogenesis of posttraumatic stress disorder …
A review of molecular imaging of glutamate receptors
JH Kim, J Marton, SM Ametamey, P Cumming - Molecules, 2020 - mdpi.com
Molecular imaging with positron emission tomography (PET) and single photon emission
computed tomography (SPECT) is a well-established and important in vivo technique to …
computed tomography (SPECT) is a well-established and important in vivo technique to …
Genetic and neuroimaging approaches to understanding post-traumatic stress disorder
Post-traumatic stress disorder (PTSD) is a highly disabling condition, increasingly
recognized as both a disorder of mental health and social burden, but also as an anxiety …
recognized as both a disorder of mental health and social burden, but also as an anxiety …