Amyloid-beta (Aβ) plays an important role in the pathogenesis of Alzheimer's disease.
Aberrant Aβ accumulation induces neuroinflammation, cerebrovascular alterations, and …

Genome-wide association studies have demonstrated significant links between human brain
structure and common DNA variants. Similar studies with rodents have been challenging …

The development and characterization of new improved animal models is pivotal in
Alzheimer's Disease (AD) research, since valid models enable the identification of early …

Subcortical white matter (WM) stroke accounts for 25% of all strokes and is the second
leading cause of dementia. Despite such clinical importance, we still do not have an …

Mesoscale diffusion magnetic resonance imaging (MRI) endeavors to bridge the gap
between macroscopic white matter tractography and microscopic studies investigating the …

Abstract Alzheimer's disease (AD), a widely studied neurodegenerative disorder, poses
significant research challenges due to its high prevalence and complex etiology. Age, a …

In this study, we assessed the evolution of diffusion MRI (dMRI) derived markers from
different white matter models as progressive neurodegeneration occurs in transgenic …

The understanding of human and non-human microstructural brain alterations in the course
of neurodegenerative diseases has substantially improved by the non-invasive magnetic …

A number of computational techniques have been lately devised to image the Ensemble
Average Propagator (EAP) within the white matter of the brain, propelled by the deployment …

In diffusion MRI, the Ensemble Average diffusion Propagator (EAP) provides relevant micro-
structural information and meaningful descriptive maps of the white matter previously …