[HTML][HTML] The scientific case for brain simulations
A key element of the European Union's Human Brain Project (HBP) and other large-scale
brain research projects is the simulation of large-scale model networks of neurons. Here, we …
brain research projects is the simulation of large-scale model networks of neurons. Here, we …
[HTML][HTML] Network dynamics of coupled oscillators and phase reduction techniques
Investigating the dynamics of a network of oscillatory systems is a timely and urgent topic.
Phase synchronization has proven paradigmatic to study emergent collective behavior …
Phase synchronization has proven paradigmatic to study emergent collective behavior …
Burst-dependent synaptic plasticity can coordinate learning in hierarchical circuits
Synaptic plasticity is believed to be a key physiological mechanism for learning. It is well
established that it depends on pre-and postsynaptic activity. However, models that rely …
established that it depends on pre-and postsynaptic activity. However, models that rely …
Biological constraints on neural network models of cognitive function
Neural network models are potential tools for improving our understanding of complex brain
functions. To address this goal, these models need to be neurobiologically realistic …
functions. To address this goal, these models need to be neurobiologically realistic …
Performance comparison of the digital neuromorphic hardware SpiNNaker and the neural network simulation software NEST for a full-scale cortical microcircuit model
The digital neuromorphic hardware SpiNNaker has been developed with the aim of
enabling large-scale neural network simulations in real time and with low power …
enabling large-scale neural network simulations in real time and with low power …
Neuronal circuits in barrel cortex for whisker sensory perception
The array of whiskers on the snout provides rodents with tactile sensory information relating
to the size, shape and texture of objects in their immediate environment. Rodents can use …
to the size, shape and texture of objects in their immediate environment. Rodents can use …
NREM sleep in the rodent neocortex and hippocampus reflects excitable dynamics
During non-rapid eye movement (NREM) sleep, neuronal populations in the mammalian
forebrain alternate between periods of spiking and inactivity. Termed the slow oscillation in …
forebrain alternate between periods of spiking and inactivity. Termed the slow oscillation in …
Biologically realistic mean-field models of conductance-based networks of spiking neurons with adaptation
Accurate population models are needed to build very large-scale neural models, but their
derivation is difficult for realistic networks of neurons, in particular when nonlinear properties …
derivation is difficult for realistic networks of neurons, in particular when nonlinear properties …
Firing rate equations require a spike synchrony mechanism to correctly describe fast oscillations in inhibitory networks
Recurrently coupled networks of inhibitory neurons robustly generate oscillations in the
gamma band. Nonetheless, the corresponding Wilson-Cowan type firing rate equation for …
gamma band. Nonetheless, the corresponding Wilson-Cowan type firing rate equation for …
[HTML][HTML] Open source brain: a collaborative resource for visualizing, analyzing, simulating, and develo** standardized models of neurons and circuits
Computational models are powerful tools for exploring the properties of complex biological
systems. In neuroscience, data-driven models of neural circuits that span multiple scales are …
systems. In neuroscience, data-driven models of neural circuits that span multiple scales are …