Understanding COVID-19-associated coagulopathy

EM Conway, N Mackman, RQ Warren… - Nature Reviews …, 2022 - nature.com
Abstract COVID-19-associated coagulopathy (CAC) is a life-threatening complication of
SARS-CoV-2 infection. However, the underlying cellular and molecular mechanisms driving …

Post-COVID-19 depressive symptoms: epidemiology, pathophysiology, and pharmacological treatment

MG Mazza, M Palladini, S Poletti, F Benedetti - CNS drugs, 2022 - Springer
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic is still spreading worldwide
over 2 years since its outbreak. The psychopathological implications in COVID-19 survivors …

Acute and postacute sequelae associated with SARS-CoV-2 reinfection

B Bowe, Y **e, Z Al-Aly - Nature medicine, 2022 - nature.com
First infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
associated with increased risk of acute and postacute death and sequelae in various organ …

Long-term neurologic outcomes of COVID-19

E Xu, Y **e, Z Al-Aly - Nature medicine, 2022 - nature.com
The neurologic manifestations of acute COVID-19 are well characterized, but a
comprehensive evaluation of postacute neurologic sequelae at 1 year has not been …

Long COVID after breakthrough SARS-CoV-2 infection

Z Al-Aly, B Bowe, Y **e - Nature medicine, 2022 - nature.com
The post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection—also referred to as Long COVID—have been described, but whether …

Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

M Taquet, Z Skorniewska, A Hampshire… - Nature medicine, 2023 - nature.com
Post-COVID cognitive deficits, including 'brain fog', are clinically complex, with both objective
and subjective components. They are common and debilitating, and can affect the ability to …

[HTML][HTML] Virus exposure and neurodegenerative disease risk across national biobanks

KS Levine, HL Leonard, C Blauwendraat, H Iwaki… - Neuron, 2023 - cell.com
With recent findings connecting the Epstein-Barr virus to an increased risk of multiple
sclerosis and growing concerns regarding the neurological impact of the coronavirus …

[HTML][HTML] Olfactory dysfunction in COVID-19: new insights into the underlying mechanisms

R Butowt, K Bilinska, CS von Bartheld - Trends in Neurosciences, 2023 - cell.com
The mechanisms of olfactory dysfunction in COVID-19 are still unclear. In this review, we
examine potential mechanisms that may explain why the sense of smell is lost or altered …

[HTML][HTML] Fibrin drives thromboinflammation and neuropathology in COVID-19

JK Ryu, Z Yan, M Montano, EG Sozmen, K Dixit… - Nature, 2024 - nature.com
Life-threatening thrombotic events and neurological symptoms are prevalent in COVID-19
and are persistent in patients with long COVID experiencing post-acute sequelae of SARS …

Designing the next-generation clinical care pathway for Alzheimer's disease

H Hampel, R Au, S Mattke, WM van der Flier, P Aisen… - Nature Aging, 2022 - nature.com
The reconceptualization of Alzheimer's disease (AD) as a clinical and biological construct
has facilitated the development of biomarker-guided, pathway-based targeted therapies …