Habit modification in pharmaceutical crystallization: A review
Besides size and purity, habit represents a critical quality attribute of pharmaceutical
crystals, influencing efficiencies of downstream processing steps and final drug product's …
crystals, influencing efficiencies of downstream processing steps and final drug product's …
Continuous crystallization and its potential use in drug substance Manufacture: A review
Interest in the continuous manufacturing in the pharmaceutical industry for the production of
Active Pharmaceutical Ingredients (API's) has greatly increased in recent years. This has led …
Active Pharmaceutical Ingredients (API's) has greatly increased in recent years. This has led …
Recent progress in continuous crystallization of pharmaceutical products: precise preparation and control
Crystallization, as a solid–liquid separation process, is employed to purify and isolate a
great diversity of crystalline pharmaceutical products. In recent years, continuous …
great diversity of crystalline pharmaceutical products. In recent years, continuous …
Membrane-cooling coupled crystallization with zero solvent discharge for spherical HMX: Process design, growth kinetics and mechanism
T Wang, Y Wang, S Hao, S Zhang, R Gou, H Li… - Chemical Engineering …, 2023 - Elsevier
The simultaneous achievement of crystal characteristics control and environmentally benign
is challenging the formulation processing of energetic materials (EMs). Herein, a membrane …
is challenging the formulation processing of energetic materials (EMs). Herein, a membrane …
Enabling precision manufacturing of active pharmaceutical ingredients: workflow for seeded cooling continuous crystallisations
CJ Brown, T McGlone, S Yerdelen… - … Systems Design & …, 2018 - pubs.rsc.org
Continuous manufacturing is widely used for the production of commodity products.
Currently, it is attracting increasing interest from the pharmaceutical industry and regulatory …
Currently, it is attracting increasing interest from the pharmaceutical industry and regulatory …
Monitoring polymer flocculation in oil sands tailings: A population balance model approach
V Vajihinejad, JBP Soares - Chemical Engineering Journal, 2018 - Elsevier
Oil sands mature fine tailings are stable suspensions of clay particles and residual bitumen
in an alkaline aqueous medium. They are formed when bitumen is extracted from oil sands …
in an alkaline aqueous medium. They are formed when bitumen is extracted from oil sands …
Insights into membrane crystallization: A sustainable tool for value added product recovery from effluent streams
Worldwide waste valorization and recovery of non-utilized components/unreacted
compounds/side streams/byproducts are being researched upon. These are indispensable …
compounds/side streams/byproducts are being researched upon. These are indispensable …
Crystal growth kinetics of an industrial active pharmaceutical ingredient: Implications of different representations of supersaturation and simultaneous growth …
GL Quilló, S Bhonsale, B Gielen… - Crystal Growth & …, 2021 - ACS Publications
The crystal growth kinetics of a proprietary active pharmaceutical ingredient (API) was
investigated by isothermal seeded batch de-supersaturation experiments in solvent mixtures …
investigated by isothermal seeded batch de-supersaturation experiments in solvent mixtures …
Modeling of nucleation, growth, and dissolution of paracetamol in ethanol solution for unseeded batch cooling crystallization with temperature-cycling strategy
Controlling crystal size distributions is critical to ensure the quality of products and
operational efficiency for downstream processing. In batch cooling crystallization …
operational efficiency for downstream processing. In batch cooling crystallization …
Finite volume approach for fragmentation equation and its mathematical analysis
This work is focused on develo** a finite volume scheme for approximating a
fragmentation equation. The mathematical analysis is discussed in detail by examining …
fragmentation equation. The mathematical analysis is discussed in detail by examining …