Recent trends in protein and peptide-based biomaterials for advanced drug delivery

A Varanko, S Saha, A Chilkoti - Advanced drug delivery reviews, 2020‏ - Elsevier
Engineering protein and peptide-based materials for drug delivery applications has gained
momentum due to their biochemical and biophysical properties over synthetic materials …

Protein assembly: versatile approaches to construct highly ordered nanostructures

Q Luo, C Hou, Y Bai, R Wang, J Liu - Chemical Reviews, 2016‏ - ACS Publications
Nature endows life with a wide variety of sophisticated, synergistic, and highly functional
protein assemblies. Following Nature's inspiration to assemble protein building blocks into …

[HTML][HTML] Self-assembling peptides and their application in the treatment of diseases

S Lee, THT Trinh, M Yoo, J Shin, H Lee, J Kim… - International journal of …, 2019‏ - mdpi.com
Self-assembling peptides are biomedical materials with unique structures that are formed in
response to various environmental conditions. Governed by their physicochemical …

Protein intrinsic disorder-based liquid–liquid phase transitions in biological systems: Complex coacervates and membrane-less organelles

VN Uversky - Advances in colloid and interface science, 2017‏ - Elsevier
It is clear now that eukaryotic cells contain numerous membrane-less organelles, many of
which are formed in response to changes in the cellular environment. Being typically liquid …

Applications of elastin-like polypeptides in drug delivery

SR MacEwan, A Chilkoti - Journal of Controlled Release, 2014‏ - Elsevier
Elastin-like polypeptides (ELPs) are biopolymers inspired by human elastin. Their lower
critical solution temperature phase transition behavior and biocompatibility make them …

Chemical components for the design of temperature-responsive vesicles as cancer therapeutics

Z Al-Ahmady, K Kostarelos - Chemical reviews, 2016‏ - ACS Publications
In this Review, we attempt to offer a thorough description of all of the chemical components
and the rationale behind the design of temperature-sensitive vesicle systems, as well as the …

Designing protein-based biomaterials for medical applications

JE Gagner, W Kim, EL Chaikof - Acta biomaterialia, 2014‏ - Elsevier
Biomaterials produced by nature have been honed through billions of years, evolving
exquisitely precise structure–function relationships that scientists strive to emulate …

[HTML][HTML] Elastin-like polypeptide-based micelles as a promising platform in nanomedicine

J van Strien, O Escalona-Rayo, W Jiskoot… - Journal of Controlled …, 2023‏ - Elsevier
New and improved nanomaterials are constantly being developed for biomedical purposes.
Nanomaterials based on elastin-like polypeptides (ELPs) have increasingly shown potential …

Engineering the architecture of elastin‐like polypeptides: from unimers to hierarchical self‐assembly

S Saha, S Banskota, S Roberts, N Kirmani… - Advanced …, 2020‏ - Wiley Online Library
Well‐defined tunable nanostructures formed through the hierarchical self‐assembly of
peptide building blocks have drawn significant attention due to their potential applications in …

Micellar self-assembly of recombinant resilin-/elastin-like block copolypeptides

I Weitzhandler, M Dzuricky, I Hoffmann… - …, 2017‏ - ACS Publications
Reported here is the synthesis of perfectly sequence defined, monodisperse diblock
copolypeptides of hydrophilic elastin-like and hydrophobic resilin-like polypeptide blocks …