Estrogens play an important role in the regulation of normal physiology, aging and many
disease states. Although the nuclear estrogen receptors have classically been described to …

Metabolic syndrome (MetS) is a leading public health and clinical challenge worldwide.
MetS represents a group of interrelated risk factors that predict cardiovascular diseases …

Sex differences in human health and disease can range from undetectable to profound.
Differences in brain tumor rates and outcome are evident in males and females throughout …

High-density lipoprotein (HDL) is considered an anti-atherogenic lipoprotein species due to
its role in reverse cholesterol transport. HDL delivers cholesterol esters to the liver through …

Diabetic cardiomyopathy is the most common chronic disease in postmenopausal women,
but the mechanism (s) is unclear. G-protein coupled receptor 30 (GPR30) is one of the …

Background & Aims: G protein-coupled receptor 30 (GPR30) is a recently de-orphanized
estrogen receptor that mediates the effects of estrogens on different cells. It has been …

Objective: To investigate differences in subclinical coronary atherosclerotic plaque and
markers of immune activation among HIV-infected and non-HIV-infected women categorized …

Estradiol (E2) is a steroid hormone whose physiological actions are mainly mediated by its
interaction with intracellular estrogen receptors (ER) leading to modification on the mRNA …

Objective We intended to identify the potential key biomarker and pathways that correlated
with infiltrating immune cells during the pathogenesis of intracranial aneurysms (IA), to …

Estrogens have the potential to afford atheroprotection, to prevent excess adiposity and its
metabolic complications including insulin resistance, and to lessen hepatic steatosis …