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Dendrimers: A versatile nanocarrier for drug delivery and targeting
Dendrimers are novel polymeric nanoarchitectures characterized by hyper-branched 3D-
structure having multiple functional groups on the surface that increases their functionality …
structure having multiple functional groups on the surface that increases their functionality …
Nanoparticle-based drug delivery system: the magic bullet for the treatment of chronic pulmonary diseases
S Pramanik, S Mohanto, R Manne… - Molecular …, 2021 - ACS Publications
Chronic pulmonary diseases encompass different persistent and lethal diseases, including
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …
Poly (amidoamine)(PAMAM) dendrimer mediated delivery of drug and pDNA/siRNA for cancer therapy
J Li, H Liang, J Liu, Z Wang - International journal of pharmaceutics, 2018 - Elsevier
Abstract Poly (amidoamine)(PAMAM) dendrimers are well-defined, highly branched
macromolecules with numerous active amine groups on the surface. Because of their …
macromolecules with numerous active amine groups on the surface. Because of their …
Mechanisms and challenges of nanocarriers as non-viral vectors of therapeutic genes for enhanced pulmonary delivery
H Wang, L Qin, X Zhang, J Guan, S Mao - Journal of Controlled Release, 2022 - Elsevier
With the rapid development of biopharmaceuticals and the outbreak of COVID-19, the world
has ushered in a frenzy to develop gene therapy. Therefore, therapeutic genes have …
has ushered in a frenzy to develop gene therapy. Therefore, therapeutic genes have …
Inhalable nanoparticle-based dry powder formulations for respiratory diseases: challenges and strategies for translational research
The emergence of novel respiratory infections (eg, COVID-19) and expeditious development
of nanoparticle-based COVID-19 vaccines have recently reignited considerable interest in …
of nanoparticle-based COVID-19 vaccines have recently reignited considerable interest in …
Nanotechnology-assisted metered-dose inhalers (MDIs) for high-performance pulmonary drug delivery applications
Purpose Respiratory disorders pose a major threat to the morbidity and mortality to public
health. Here we reviewed the nanotechnology based pulmonary drug delivery using …
health. Here we reviewed the nanotechnology based pulmonary drug delivery using …
Dry powder pharmaceutical biologics for inhalation therapy
Therapeutic biologics such as genes, peptides, proteins, virus and cells provide clinical
benefits and are becoming increasingly important tools in respiratory medicine. Pulmonary …
benefits and are becoming increasingly important tools in respiratory medicine. Pulmonary …
Trends in targeted delivery of nanomaterials in colon cancer diagnosis and treatment
Colon cancer is an adenocarcinoma, which subsequently develops into malignant tumors, if
not treated properly. The current colon cancer therapy mainly revolves around …
not treated properly. The current colon cancer therapy mainly revolves around …
[HTML][HTML] Lipids and polymers in pharmaceutical technology: Lifelong companions
J Siepmann, A Faham, SD Clas, BJ Boyd… - International journal of …, 2019 - Elsevier
In pharmaceutical technology, lipids and polymers are considered pillar excipients for the
fabrication of most dosage forms, irrespective of the administration route. They play various …
fabrication of most dosage forms, irrespective of the administration route. They play various …
[HTML][HTML] RNAi therapies: expanding applications for extrahepatic diseases and overcoming delivery challenges
The era of RNA medicine has become a reality with the success of messenger RNA (mRNA)
vaccines against COVID-19 and the approval of several RNA interference (RNAi) agents in …
vaccines against COVID-19 and the approval of several RNA interference (RNAi) agents in …