Dendrimers: A versatile nanocarrier for drug delivery and targeting

AP Sherje, M Jadhav, BR Dravyakar… - International journal of …, 2018 - Elsevier
Dendrimers are novel polymeric nanoarchitectures characterized by hyper-branched 3D-
structure having multiple functional groups on the surface that increases their functionality …

Nanoparticle-based drug delivery system: the magic bullet for the treatment of chronic pulmonary diseases

S Pramanik, S Mohanto, R Manne… - Molecular …, 2021 - ACS Publications
Chronic pulmonary diseases encompass different persistent and lethal diseases, including
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …

Poly (amidoamine)(PAMAM) dendrimer mediated delivery of drug and pDNA/siRNA for cancer therapy

J Li, H Liang, J Liu, Z Wang - International journal of pharmaceutics, 2018 - Elsevier
Abstract Poly (amidoamine)(PAMAM) dendrimers are well-defined, highly branched
macromolecules with numerous active amine groups on the surface. Because of their …

Mechanisms and challenges of nanocarriers as non-viral vectors of therapeutic genes for enhanced pulmonary delivery

H Wang, L Qin, X Zhang, J Guan, S Mao - Journal of Controlled Release, 2022 - Elsevier
With the rapid development of biopharmaceuticals and the outbreak of COVID-19, the world
has ushered in a frenzy to develop gene therapy. Therefore, therapeutic genes have …

Inhalable nanoparticle-based dry powder formulations for respiratory diseases: challenges and strategies for translational research

HW Chan, S Chow, X Zhang, Y Zhao, HHY Tong… - AAPS …, 2023 - Springer
The emergence of novel respiratory infections (eg, COVID-19) and expeditious development
of nanoparticle-based COVID-19 vaccines have recently reignited considerable interest in …

Nanotechnology-assisted metered-dose inhalers (MDIs) for high-performance pulmonary drug delivery applications

R Kumar, P Mehta, KR Shankar, MAK Rajora… - Pharmaceutical …, 2022 - Springer
Purpose Respiratory disorders pose a major threat to the morbidity and mortality to public
health. Here we reviewed the nanotechnology based pulmonary drug delivery using …

Dry powder pharmaceutical biologics for inhalation therapy

RYK Chang, MYT Chow, D Khanal, D Chen… - Advanced Drug Delivery …, 2021 - Elsevier
Therapeutic biologics such as genes, peptides, proteins, virus and cells provide clinical
benefits and are becoming increasingly important tools in respiratory medicine. Pulmonary …

Trends in targeted delivery of nanomaterials in colon cancer diagnosis and treatment

FA Khan, R Albalawi, FH Pottoo - Medicinal research reviews, 2022 - Wiley Online Library
Colon cancer is an adenocarcinoma, which subsequently develops into malignant tumors, if
not treated properly. The current colon cancer therapy mainly revolves around …

[HTML][HTML] Lipids and polymers in pharmaceutical technology: Lifelong companions

J Siepmann, A Faham, SD Clas, BJ Boyd… - International journal of …, 2019 - Elsevier
In pharmaceutical technology, lipids and polymers are considered pillar excipients for the
fabrication of most dosage forms, irrespective of the administration route. They play various …

[HTML][HTML] RNAi therapies: expanding applications for extrahepatic diseases and overcoming delivery challenges

JW Lee, MK Shim, H Kim, H Jang, Y Lee… - Advanced Drug Delivery …, 2023 - Elsevier
The era of RNA medicine has become a reality with the success of messenger RNA (mRNA)
vaccines against COVID-19 and the approval of several RNA interference (RNAi) agents in …