Genetic diversity loss in the Anthropocene

M Exposito-Alonso, TR Booker, L Czech, L Gillespie… - Science, 2022‏ - science.org
Anthropogenic habitat loss and climate change are reducing species' geographic ranges,
increasing extinction risk and losses of species' genetic diversity. Although preserving …

The utility of Drosophila melanogaster as a fungal infection model

CD Mpamhanga, I Kounatidis - Frontiers in Immunology, 2024‏ - frontiersin.org
Invasive fungal diseases have profound effects upon human health and are on increase
globally. The World Health Organization (WHO) in 2022 published the fungal priority list …

From sub-Saharan Africa to China: Evolutionary history and adaptation of Drosophila melanogaster revealed by population genomics

J Chen, C Liu, W Li, W Zhang, Y Wang, AG Clark… - Science …, 2024‏ - science.org
Drosophila melanogaster is a widely used model organism for studying environmental
adaptation. However, the genetic diversity of populations in Asia is poorly understood …

Temperature effects on cellular host-microbe interactions explain continent-wide endosymbiont prevalence

MTJ Hague, JD Shropshire, CN Caldwell, JP Statz… - Current Biology, 2022‏ - cell.com
Endosymbioses influence host physiology, reproduction, and fitness, but these relationships
require efficient microbe transmission between host generations to persist. Maternally …

De novo assembly of transcriptomes and differential gene expression analysis using short-read data from emerging model organisms–a brief guide

DJ Jackson, N Cerveau, N Posnien - Frontiers in Zoology, 2024‏ - Springer
Many questions in biology benefit greatly from the use of a variety of model systems. High-
throughput sequencing methods have been a triumph in the democratization of diverse …

[PDF][PDF] An ancestral balanced inversion polymorphism confers global adaptation

M Kapun, ED Mitchell, TJ Kawecki… - … biology and evolution, 2023‏ - academic.oup.com
Since the pioneering work of Dobzhansky in the 1930s and 1940s, many chromosomal
inversions have been identified, but how they contribute to adaptation remains poorly …

Population genomics reveals mechanisms and dynamics of de novo expressed open reading frame emergence in Drosophila melanogaster

A Grandchamp, L Kühl, M Lebherz… - Genome …, 2023‏ - genome.cshlp.org
Novel genes are essential for evolutionary innovations and differ substantially even between
closely related species. Recently, multiple studies across many taxa showed that some …

[PDF][PDF] A cosmopolitan inversion facilitates seasonal adaptation in overwintering Drosophila

JCB Nunez, BA Lenhart, A Bangerter, CS Murray… - Genetics, 2024‏ - academic.oup.com
Fluctuations in the strength and direction of natural selection through time are a ubiquitous
feature of life on Earth. One evolutionary outcome of such fluctuations is adaptive tracking …

A Population Genomic Assessment of Three Decades of Evolution in a Natural Drosophila Population

JD Lange, H Bastide, JB Lack… - Molecular Biology and …, 2022‏ - academic.oup.com
Population genetics seeks to illuminate the forces sha** genetic variation, often based on
a single snapshot of genomic variation. However, utilizing multiple sampling times to study …

Genomes from historical Drosophila melanogaster specimens illuminate adaptive and demographic changes across more than 200 years of evolution

M Shpak, HR Ghanavi, JD Lange, JE Pool… - PLoS …, 2023‏ - journals.plos.org
The ability to perform genomic sequencing on long-dead organisms is opening new frontiers
in evolutionary research. These opportunities are especially notable in the case of museum …