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Smoothed particle hydrodynamics (SPH) for complex fluid flows: Recent developments in methodology and applications
Computer modeling of complex fluid flows usually presents great challenges for
conventional grid-based numerical methods. Smoothed particle hydrodynamics (SPH) is a …
conventional grid-based numerical methods. Smoothed particle hydrodynamics (SPH) is a …
Blood flow in the microcirculation
The microcirculation is an extensive network of microvessels that distributes blood flow
throughout living tissues. Reynolds numbers are much less than 1, and the equations of …
throughout living tissues. Reynolds numbers are much less than 1, and the equations of …
A computational study of red blood cell deformability effect on hemodynamic alteration in capillary vessel networks
Capillary blood vessels, the smallest vessels in the body, form an intricate network with
constantly bifurcating, merging and winding vessels. Red blood cells (RBCs) must navigate …
constantly bifurcating, merging and winding vessels. Red blood cells (RBCs) must navigate …
[HTML][HTML] Regardless of etiology, progressive renal disease causes ultrastructural and functional alterations of peritubular capillaries
Progressive renal diseases are associated with rarefaction of peritubular capillaries, but the
ultrastructural and functional alterations of the microvasculature are not well described. To …
ultrastructural and functional alterations of the microvasculature are not well described. To …
The influence of size, shape and vessel geometry on nanoparticle distribution
Nanoparticles (NPs) are emerging as promising carrier platforms for targeted drug delivery
and imaging probes. To evaluate the delivery efficiency, it is important to predict the …
and imaging probes. To evaluate the delivery efficiency, it is important to predict the …
A computational approach to modeling cellular-scale blood flow in complex geometry
We present a computational methodology for modeling cellular-scale blood flow in arbitrary
and highly complex geometry. Our approach is based on immersed-boundary methods …
and highly complex geometry. Our approach is based on immersed-boundary methods …
[HTML][HTML] Analysis of red blood cell partitioning at bifurcations in simulated microvascular networks
Partitioning of red blood cells (RBCs) at vascular bifurcations has been studied over many
decades using in vivo, in vitro, and theoretical models. These studies have shown that RBCs …
decades using in vivo, in vitro, and theoretical models. These studies have shown that RBCs …
The cell-free layer in microvascular blood flow
This review discusses the cell-free layer at the wall of the microcirculatory vessels with
emphasis on the influence of blood rheological parameters on its formation as well as its …
emphasis on the influence of blood rheological parameters on its formation as well as its …
Mechanisms of coronary sinus reducer for treatment of myocardial ischemia: in silico study
The coronary sinus reducer (CSR) is an emerging medical device for treating patients with
refractory angina, often associated with myocardial ischemia. Patients implanted with CSR …
refractory angina, often associated with myocardial ischemia. Patients implanted with CSR …
Direct numerical simulation of cellular-scale blood flow in 3D microvascular networks
We present, to our knowledge, the first direct numerical simulation of 3D cellular-scale blood
flow in physiologically realistic microvascular networks. The vascular networks are designed …
flow in physiologically realistic microvascular networks. The vascular networks are designed …