The brain reward circuitry in mood disorders
Mood disorders are common and debilitating conditions characterized in part by profound
deficits in reward-related behavioural domains. A recent literature has identified important …
deficits in reward-related behavioural domains. A recent literature has identified important …
Stress and the dopaminergic reward system
JH Baik - Experimental & molecular medicine, 2020 - nature.com
Dopamine regulates reward-related behavior through the mesolimbic dopaminergic
pathway. Stress affects dopamine levels and dopaminergic neuronal activity in the …
pathway. Stress affects dopamine levels and dopaminergic neuronal activity in the …
Interface engineering of highly efficient perovskite solar cells
Advancing perovskite solar cell technologies toward their theoretical power conversion
efficiency (PCE) requires delicate control over the carrier dynamics throughout the entire …
efficiency (PCE) requires delicate control over the carrier dynamics throughout the entire …
Frontostriatal salience network expansion in individuals in depression
Decades of neuroimaging studies have shown modest differences in brain structure and
connectivity in depression, hindering mechanistic insights or the identification of risk factors …
connectivity in depression, hindering mechanistic insights or the identification of risk factors …
Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation
INTRODUCTION Depression is an episodic form of mental illness, yet the circuit-level
mechanisms driving the induction, remission, and recurrence of depressive episodes over …
mechanisms driving the induction, remission, and recurrence of depressive episodes over …
Long-range and local circuits for top-down modulation of visual cortex processing
Top-down modulation of sensory processing allows the animal to select inputs most relevant
to current tasks. We found that the cingulate (Cg) region of the mouse frontal cortex …
to current tasks. We found that the cingulate (Cg) region of the mouse frontal cortex …
Pathogenesis of depression: insights from human and rodent studies
Major depressive disorder (MDD) will affect one out of every five people in their lifetime and
is the leading cause of disability worldwide. Nevertheless, mechanisms associated with the …
is the leading cause of disability worldwide. Nevertheless, mechanisms associated with the …
Prefrontal cortical regulation of brainwide circuit dynamics and reward-related behavior
INTRODUCTION The drive to seek and experience reward is conserved across species and,
in mammals, involves interactions between subcortical dopaminergic systems and limbic …
in mammals, involves interactions between subcortical dopaminergic systems and limbic …
Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression
Enhanced glutamatergic transmission in the nucleus accumbens (NAc), a region critical for
reward and motivation, has been implicated in the pathophysiology of depression; however …
reward and motivation, has been implicated in the pathophysiology of depression; however …
Dendritic spines in depression: what we learned from animal models
H Qiao, MX Li, C Xu, HB Chen, SC An… - Neural plasticity, 2016 - Wiley Online Library
Depression, a severe psychiatric disorder, has been studied for decades, but the underlying
mechanisms still remain largely unknown. Depression is closely associated with alterations …
mechanisms still remain largely unknown. Depression is closely associated with alterations …