Dopamine regulates reward-related behavior through the mesolimbic dopaminergic
pathway. Stress affects dopamine levels and dopaminergic neuronal activity in the …

Depression is an episodic form of mental illness characterized by mood state transitions with
poorly understood neurobiological mechanisms. Antidepressants reverse the effects of …

Decades of neuroimaging studies have shown modest differences in brain structure and
connectivity in depression, hindering mechanistic insights or the identification of risk factors …

INTRODUCTION Depression is an episodic form of mental illness, yet the circuit-level
mechanisms driving the induction, remission, and recurrence of depressive episodes over …

Hypothalamic AgRP and POMC neurons are conventionally viewed as the yin and yang of
the body's energy status, since they act in an opposite manner to modulate appetite and …

Recent clinical and preclinical evidence suggests that psychedelics and entactogens may
produce both rapid and sustained therapeutic effects across several indications. Currently …

Major depressive disorder (MDD) will affect one out of every five people in their lifetime and
is the leading cause of disability worldwide. Nevertheless, mechanisms associated with the …

Mood disorders are common and debilitating conditions characterized in part by profound
deficits in reward-related behavioural domains. A recent literature has identified important …

Advancing perovskite solar cell technologies toward their theoretical power conversion
efficiency (PCE) requires delicate control over the carrier dynamics throughout the entire …

INTRODUCTION The drive to seek and experience reward is conserved across species and,
in mammals, involves interactions between subcortical dopaminergic systems and limbic …