There is now strong evidence of progressive neuropathological processes in bipolar
disorder (BD). On this basis, the current understanding of the neurobiology of BD has shifted …

A comprehensive literature search was performed to collate evidence of mitochondrial
dysfunction in autism spectrum disorders (ASDs) with two primary objectives. First, features …

Human and animal studies suggest an intriguing link between mitochondrial diseases and
depression. Although depression has historically been linked to alterations in …

Background Completed suicide is a major cause of death in bipolar disorder (BD) patients.
Objective The aim of this paper is to provide an overall review of the existing literature of …

N-acetylcysteine (NAC) is recognized for its role in acetaminophen overdose and as a
mucolytic. Over the past decade, there has been growing evidence for the use of NAC in …

N-Acetylcysteine (NAC) targets a diverse array of factors germane to the pathophysiology of
multiple neuropsychiatric disorders including glutamatergic transmission, the antioxidant …

Schizophrenia is a severe, complex mental disorder characterized by a combination of
positive symptoms, negative symptoms, and impaired cognitive function. Schizophrenia is …

BACKGROUND: Oxidative stress is thought to mediate neuropathological processes of a
number of neuropsychiatric disorders and recent data suggest that oxidative stress may be …

Lithium has been used for the treatment of bipolar disorder (BD) for the last sixty or more
years, and recent studies with more reliable designs and updated guidelines have …

Context Accumulating evidence suggests that mitochondrial dysfunction and oxidative stress
contribute to the pathogenesis of bipolar disorder and schizophrenia. It remains unclear …