Respiratory sequelae of COVID-19: pulmonary and extrapulmonary origins, and approaches to clinical care and rehabilitation

SJ Singh, MM Baldwin, E Daynes, RA Evans… - The Lancet …, 2023 - thelancet.com
Although the exact prevalence of post-COVID-19 condition (also known as long COVID) is
unknown, more than a third of patients with COVID-19 develop symptoms that persist for …

[HTML][HTML] Systemic corticosteroids in asthma: a call to action from World Allergy Organization and Respiratory Effectiveness Group

ER Bleecker, M Al-Ahmad, L Bjermer… - World Allergy …, 2022 - Elsevier
Systemic corticosteroids (SCS) are a highly effective treatment for acute exacerbations and
long-term symptom control in asthma. Long-term SCS use is highly prevalent across all …

The evolution of a large biobank at Mass General Brigham

NT Boutin, SB Schecter, EF Perez… - Journal of Personalized …, 2022 - mdpi.com
The Mass General Brigham Biobank (formerly Partners HealthCare Biobank) is a large
repository of biospecimens and data linked to extensive electronic health record data and …

Association of dose of inhaled corticosteroids and frequency of adverse events

CI Bloom, F Yang, R Hubbard, A Majeed… - American Journal of …, 2025 - atsjournals.org
Rationale: Inhaled corticosteroids (ICSs) are the cornerstone of asthma treatment and
significantly improve morbidity and mortality. Adverse effects of oral corticosteroids are well …

European Respiratory Society short guidelines for the use of as-needed ICS/formoterol in mild asthma

A Papi, DS Ferreira, I Agache, E Baraldi… - European …, 2023 - Eur Respiratory Soc
Recent clinical trials of as-needed fixed-dose combination of inhaled corticosteroid
(ICS)/formoterol have provided new evidence that may warrant a reconsideration of current …

[HTML][HTML] New approaches in childhood asthma treatment

R Castagnoli, I Brambilla, M Giovannini… - Current Opinion in …, 2023 - journals.lww.com
With the expanding landscape of novel therapeutic approaches for pediatric asthma, further
evidence is needed to help clinicians choose the best option for patients, particularly those …

Microbiome modifications by steroids during viral exacerbation of asthma and in healthy mice

K Yagi, AD Ethridge, NR Falkowski… - … of Physiology-Lung …, 2024 - journals.physiology.org
In the present studies, the assessment of how viral exacerbation of asthmatic responses with
and without pulmonary steroid treatment alters the microbiome in conjunction with immune …

Metabolomics and lipidomics strategies in modern drug discovery and development

G Astarita, RS Kelly, J Lasky-Su - Drug Discovery Today, 2023 - Elsevier
Metabolomics and lipidomics have an increasingly pivotal role in drug discovery and
development. In the context of drug discovery, monitoring changes in the levels or …

[HTML][HTML] Severe asthma standard-of-care background medication reduction with benralizumab: ANDHI in practice substudy

R Louis, TW Harrison, P Chanez, F Menzella… - The Journal of Allergy …, 2023 - Elsevier
Background The phase IIIb, randomized, parallel-group, placebo-controlled ANDHI double-
blind (DB) study extended understanding of the efficacy of benralizumab for patients with …

[HTML][HTML] A single extraction 96-well method for LC-MS/MS quantification of urinary eicosanoids, steroids and drugs

J Sieminska, J Kolmert, J Zurita, K Benkestock… - Prostaglandins & Other …, 2024 - Elsevier
Urinary eicosanoid concentrations reflect inflammatory processes in multiple diseases and
have been used as biomarkers of disease as well as suggested for patient stratification in …