Cell therapy products are frequently developed and produced without incorporating cost
considerations into process development, contributing to prohibitively costly products …

Adipose tissue senescence is implicated as a major player in obesity-and ageing-related
disorders. There is a growing body of research studying relevant mechanisms in age-related …

Background Adipose-derived stem cells (ADSCs) promote tissue regeneration and repair.
Cryoprotective agents (CPAs) protect cells from cryodamage during cryopreservation. Safe …

Background Long-term preservation of adipose tissue is crucial for clinical applications.
Researchers should consider both efficiency and biosafety when choosing a cryoprotective …

Background: Fat grafting frequently requires multiple treatments and thus repeated
liposuction to achieve treatment goals. The purpose of this study was to evaluate whether …

Background Cryopreservation of fat grafts facilitates reinjection for later use. However, low
temperature and thawing can disrupt tissues and cause lipid leakage, which raises safety …

Currently, fat transplantation occurs immediately after harvesting procedures. Because low
rates of fat graft take are well reported in the literature, many patients require multiple …

Background The survival rate of fat transplants is variable and consequently multiple
operations are often required to achieve satisfactory results. Fat cryopreservation technology …

Soft tissue regeneration remains a challenge in reconstructive surgery. So far, both
autologous fat implantations and artificial implants methods used in clinical applications …

In this chapter we consider the particular preservation storage procedures applied to a
range of cell types used to produce cell-based medicines. Specifically, it deals with the …