Mechanical deformation and death of circulating tumor cells in the bloodstream
The circulation of tumor cells through the bloodstream is a significant step in tumor
metastasis. To better understand the metastatic process, circulating tumor cell (CTC) survival …
metastasis. To better understand the metastatic process, circulating tumor cell (CTC) survival …
Computational models of cancer cell transport through the microcirculation
The transport of cancerous cells through the microcirculation during metastatic spread
encompasses several interdependent steps that are not fully understood. Computational …
encompasses several interdependent steps that are not fully understood. Computational …
Haemodynamic-dependent arrest of circulating tumour cells at large blood vessel bifurcations as new model for metastasis
Homing of circulating tumour cells (CTC) at distant sites represents a critical event in
metastasis dissemination. In addition to physical entrapment, probably responsible of the …
metastasis dissemination. In addition to physical entrapment, probably responsible of the …
Margination and adhesion dynamics of tumor cells in a real microvascular network
In tumor metastasis, the margination and adhesion of tumor cells are two critical and closely
related steps, which may determine the destination where the tumor cells extravasate to. We …
related steps, which may determine the destination where the tumor cells extravasate to. We …
3D‐Printed Centrifugal Pump Driven by Magnetic Force in Applications for Microfluidics in Biological Analysis
In recent years, microfluidic systems have been extensively utilized for biological analysis.
The integration of pumps in microfluidic systems requires precise control of liquids and effort …
The integration of pumps in microfluidic systems requires precise control of liquids and effort …
Numerical investigation on flow-induced wall shear stress variation of metastatic cancer cells in lymphatics with elastic valves
X Zhang, K Yue, X Zhang - Computer Methods in Biomechanics …, 2024 - Taylor & Francis
Hematogenous metastasis occurs when cancer cells detach from the extracellular matrix in
the primary tumor into the bloodstream or lymphatic system. Elucidating the response of …
the primary tumor into the bloodstream or lymphatic system. Elucidating the response of …
Computational analysis of cancer cell adhesion in curved vessels affected by wall shear stress for prediction of metastatic spreading
N Rahmati, N Maftoon - Frontiers in Bioengineering and …, 2024 - frontiersin.org
Introduction: The dynamics of circulating tumor cells (CTCs) within blood vessels play a
pivotal role in predicting metastatic spreading of cancer within the body. However, the …
pivotal role in predicting metastatic spreading of cancer within the body. However, the …
Establishing metrics to quantify spatial similarity in spherical and red blood cell distributions
As computational power increases and systems with millions of red blood cells can be
simulated, it is important to note that varying spatial distributions of cells may affect …
simulated, it is important to note that varying spatial distributions of cells may affect …
Epithelial and mesenchymal phenotypes determine the dynamics of circulating breast tumor cells in microfluidic capillaries under chemotherapy-induced stress
R Du, X Han, L Deng, X Wang - Biomicrofluidics, 2024 - pubs.aip.org
Circulating tumor cells (CTCs) with different epithelial and mesenchymal phenotypes play
distinct roles in the metastatic cascade. However, the influence of their phenotypic traits and …
distinct roles in the metastatic cascade. However, the influence of their phenotypic traits and …
Investigating the Influence of Heterogeneity Within Cell Types on Microvessel Network Transport
Background Current research on the biophysics of circulating tumor cells often overlooks the
heterogeneity of cell populations, focusing instead on average cellular properties. This study …
heterogeneity of cell populations, focusing instead on average cellular properties. This study …