The evolution of commercial drug delivery technologies
Drug delivery technologies have enabled the development of many pharmaceutical
products that improve patient health by enhancing the delivery of a therapeutic to its target …
products that improve patient health by enhancing the delivery of a therapeutic to its target …
[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …
commercial point of view. In order to reach the systemic circulation after oral administration …
Bioinspired adaptable indwelling microneedles for treatment of diabetic ulcers
Microneedles provide an effective strategy for transdermal drug delivery. Many endeavors
have been devoted to develo** smart microneedles that can respond to and interact with …
have been devoted to develo** smart microneedles that can respond to and interact with …
Alzheimer's and Parkinson's disease therapies in the clinic
P Chopade, N Chopade, Z Zhao… - Bioengineering & …, 2023 - Wiley Online Library
Alzheimer's disease (AD) and Parkinson's disease (PD) are the most prevalent
neurodegenerative diseases, affecting millions and costing billions each year in the United …
neurodegenerative diseases, affecting millions and costing billions each year in the United …
Engineering microneedle patches for improved penetration: analysis, skin models and factors affecting needle insertion
Transdermal microneedle (MN) patches are a promising tool used to transport a wide variety
of active compounds into the skin. To serve as a substitute for common hypodermic needles …
of active compounds into the skin. To serve as a substitute for common hypodermic needles …
Advances in oral peptide therapeutics
DJ Drucker - Nature reviews Drug discovery, 2020 - nature.com
Protein and peptide therapeutics require parenteral administration, which can be a deterrent
to medication adherence. For this reason, there have been extensive efforts to develop …
to medication adherence. For this reason, there have been extensive efforts to develop …
Peptide-based drug discovery: Current status and recent advances
Highlights•A comprehensive compilation and analysis of FDA approved and under clinical
trials peptide-based therapeutics.•Clinical trial peptides pipeline analysis reveals emerging …
trials peptide-based therapeutics.•Clinical trial peptides pipeline analysis reveals emerging …
Hydrogel-based controlled drug delivery for cancer treatment: a review
As an emerging drug carrier, hydrogels have been widely used for tumor drug delivery. A
hydrogel drug carrier can cause less severe side effects than systemic chemotherapy and …
hydrogel drug carrier can cause less severe side effects than systemic chemotherapy and …
[HTML][HTML] Oral delivery of proteins and peptides: Challenges, status quo and future perspectives
Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …
A mussel-inspired film for adhesion to wet buccal tissue and efficient buccal drug delivery
Administration of drugs via the buccal route has attracted much attention in recent years.
However, develo** systems with satisfactory adhesion under wet conditions and …
However, develo** systems with satisfactory adhesion under wet conditions and …