Colorectal cancer (CRC) is among the most lethal and prevalent malignancies in the world
and was responsible for nearly 881,000 cancer-related deaths in 2018. Surgery and …

New polymers are continuously developed for new therapeutic applications. New and
modified polymer chemistries that offer distinctive degradation and drug delivery are being …

Colorectal cancer is the third most common and the second deadliest cancer worldwide. To
date, colorectal cancer becomes one of the most important challenges of the health system …

Colorectal cancer (CRC) is the fourth leading cause of the worldwide cancer mortality.
Different molecular mechanisms have been attributed to the development and progress of …

Colorectal cancer (CRC) is the third most frequently detected type of cancer, and the second
most common cause of cancer-related mortality globally. The American Cancer Society …

Colorectal cancer (CRC), a leading cause of cancer-related mortalities globally, results from
the accumulation of multiple genetic and epigenetic alterations in the normal colonic and …

Colorectal cancer (CRC) is the third most commonly detected cancer with a serious global
health issue. The rates for incidence and mortality for CRC are alarming, especially since …

Background Immune checkpoint blockade (ICB) therapies have changed the paradigm of
cancer therapies. However, anti-tumor response of the ICB is insufficient for many patients …

Abstract Background Approximately 5.0–24.2% of colorectal cancers (CRCs) have
inactivating mutations in SMAD4, making it one of the frequently mutated genes in CRC. We …

Colorectal cancer (CRC) is one of the most common human malignancies worldwide. Along
with apoptosis and inflammation, autophagy is one of three important mechanisms in CRC …