BACKGROUND Regulated cell death is a fundamental component of numerous
physiological processes; spanning from organogenesis in utero, to normal cell turnover …

Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …

Secreted membrane-enclosed vesicles, collectively called extracellular vesicles (EVs),
which include exosomes, ectosomes, microvesicles, microparticles, apoptotic bodies and …

Acetylcholinesterase (AChE) is a key enzyme in the nervous system. It terminates nerve
impulses by catalysing the hydrolysis of neurotransmitter acetylcholine. As a specific …

Alternative splicing (AS) is a complex coordinated transcriptional regulatory mechanism. It
affects nearly 95% of all protein-coding genes and occurs in nearly all human organs …

Depression is the leading psychiatric disorder worldwide with a significant economic and
emotional strain on society. There is a need for robust biomarkers which will help improve …

To date, more than 40 different types of cells from primary cultures or cell lines have shown
AChE expression during apoptosis and after the induction apoptosis by different stimuli. It …

Mental stress modifies both cholinergic neurotransmission and alternative splicing in the
brain, via incompletely understood mechanisms. Here, we report that stress changes brain …

The developmental processes that establish the synaptic architecture of the brain while
retaining capacity for activity-dependent remodeling, are complex and involve a combination …

The neurotransmitter acetylcholine (ACh) acts as an autocrine growth factor for human lung
cancer. Several lines of evidence show that lung cancer cells express all of the proteins …