Quinoline, which consists of benzene fused with N-heterocyclic pyridine, has received
considerable attention as a core template in drug design because of its broad spectrum of …

Cancer cells have the ability of dysregulation and autonomous proliferation due to
unchecked production of definite molecules. These molecules are involved in the cell growth …

The aurora kinase is a key enzyme that is implicated in tumor growth. Research revealed
that small molecules that target aurora kinase have beneficial effects as anticancer agents …

Cancer is a wide collection of diseases and among the numerous pathways involved in
cancer pathogenesis, pathway involving epidermal growth factor receptor (EGFR) is one of …

Stenotrophomonas maltophilia is a model organism exhibiting intrinsic antibiotic resistance,
primarily due to its production of Mβ-lactamase enzymes that inactivate β-lactam antibiotics …

Quinolines have become essential to many drugs, including broad-spectrum antibiotics,
antivirus, antitubercular, and antimalarial agents. Owing to their importance in medicinal and …

Breast cancer has been one of the most challenging women's cancers and leading cause of
mortality for decades. There are several studies being conducted all the time to find a cure …

The discovery of novel chemotherapeutic agents is always challenging for researchers in
industry and academia. Among the recent promising anticancer therapeutic targets, an …

Despite decades of research, anticancer medication therapy is still largely constrained to
prevent growth and limit the spread of tumour cells. To speed up the process of finding …

The p90 ribosomal protein S6 Kinase (RSK) family belongs to Ser/Thr protein kinases that
includes four isoform RSK1-4 in mammals. The ribosomal protein S6 Kinase 1 (RSK1) is …